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merck millipore,默克密理博,16-170,Anti-Myc Tag Antibody, clone 9E10, biotin conjugate
产品名称：Anti-Myc Tag Antibody, clone 9E10, biotin conjugate
产品型号：16-170
Anti-Myc Tag Antibody, clone 9E10, biotin conjugate detects level of Myc Tag & has been published & validated for use in WB & IC.
merck millipore,默克密理博,16-170,Anti-Myc Tag Antibody, clone 9E10, biotin conjugate
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H ICC, WB M Biotin Monoclonal Antibody 描述 产品目录编号 16-170 品牌系列 Upstate
商名 - Upstate
描述 Anti-Myc Tag Antibody, clone 9E10, biotin conjugate 概述 Anti-Myc Tag antibody (05-419) conjugated to biotin 产品信息 格式 Biotin 演示 PBS and 0.05% sodium azide 应用 应用 Anti-Myc Tag Antibody, clone 9E10, biotin conjugate detects level of Myc Tag & has been published & validated for use in WB & IC. 主要应用 - Immunocytochemistry
- Western Blotting
应用说明 For use in applications in which a biotin conjugate is advantageous, such as WB and ICC. 生物信息 克隆 clone 9E10 宿主 Mouse 品种反应性 Human 抗体类型 Monoclonal Antibody Entrez基因编号 - NM_002467.3
Entrez基因汇总 The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. 基因符号 - c-Myc
- MYC
- C-MYC
UniProt编号 - P01106
UniProt汇总 FUNCTION: SwissProt: P01106 # Participates in the regulation of gene transcription. Binds DNA both in a non-specific manner and also specifically to recognizes the core sequence 5'-CAC[GA]TG-3'. Seems to activate the transcription of growth-related genes.
SIZE: 439 amino acids; 48804 Da
SUBUNIT: Efficient DNA binding requires dimerization with another bHLH protein. Binds DNA as a heterodimer with MAX. Interacts with TAF1C and SPAG9. Interacts with PARP10. Interacts with JARID1A and JARID1B.
SUBCELLULAR LOCATION: Nucleus.
PTM: Phosphorylated by PRKDC.
DISEASE: SwissProt: P01106 # Overexpression of MYC is implicated in the etiology of a variety of hematopoietic tumors. & A chromosomal aberration involving MYC may be a cause of a form of B-cell chronic lymphocytic leukemia. Translocation t(8;12)(q24;q22) with BTG1.
SIMILARITY: SwissProt: P01106 ## Contains 1 basic helix-loop-helix (bHLH) domain.产品使用声明 质量保证 routinely evaluated by immunoblot in HeLa nuclear extract and myc-tagged recombinant protein 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 1 year at 4°C 包装信息 数量 200 µg
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