• merck millipore,默克密理博,443300,MCI-186 - CAS 89-25-8 - Calbiochem
  • merck millipore,默克密理博,443300,MCI-186 - CAS 89-25-8 - Calbiochem

    产品名称:MCI-186 - CAS 89-25-8 - Calbiochem
    产品型号:443300
    A free radical scavenger and antioxidant that reduces post-ischemic brain injury.

    merck millipore,默克密理博,443300,MCI-186 - CAS 89-25-8 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,443300,MCI-186 - CAS 89-25-8 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₀H₁₀N₂O89-25-8
    描述
    概述 A free radical scavenger and antioxidant that reduces post-ischemic brain injury. Inhibits iron-dependent peroxidation in rat brain homogenates (IC50 = 15 µM). Inhibits mitochondrial permeability transition pore.
    产品目录编号 443300
    品牌系列 Calbiochem®
    同义词 3-Methyl-1-phenyl-2-pyrazolin-5-one, PMP, Edaravone
    参考
    参考 Katare, R. G., et al. 2003. Am. J. Physiol. 285, H2171.
    Kawai, H., et al. 1997. J. Pharmacol. Exp. Ther. 281, 921.
    Yamamoto, Y., et al. 1996. Redox. Report 2, 333.
    Watanabe, T., et al. 1994. J. Pharmacol. Exp. Ther. 268, 1597.
    Nishi, H., et al. 1989. Stroke 20, 1236.
    产品信息
    CAS号 89-25-8
    具有ATP竞争性 N
    形式 Cream-colored solid
    Hill配方 C₁₀H₁₀N₂O
    化学配方 C₁₀H₁₀N₂O
    Molar Mass 174.2
    可逆 N
    结构配方图像
    生物信息
    主靶 A free radical scavenger and antioxidant
    主靶IC50 15 µM inhibiting iron-dependent peroxidation in rat brain homogenates
    纯度 ≥98% by HPLC
    理化信息
    细胞可渗透 N
    溶解度 DMSO
    GHS安全信息
    RTECS UQ9625000
    安全信息
    R相 R: 22-36/37/38-43

    Harmful if swallowed.
    Irritating to eyes, respiratory system and skin.
    May cause sensitization by skin contact.
    S相 S: 26-36

    In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
    Wear suitable protective clothing.
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Harmful
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,443300,MCI-186 - CAS 89-25-8 - Calbiochem

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