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经验配方 CAS号 C₁₀H₁₀N₂O 89-25-8 描述 概述 A free radical scavenger and antioxidant that reduces post-ischemic brain injury. Inhibits iron-dependent peroxidation in rat brain homogenates (IC50 = 15 µM). Inhibits mitochondrial permeability transition pore. 产品目录编号 443300 品牌系列 Calbiochem®
同义词 3-Methyl-1-phenyl-2-pyrazolin-5-one, PMP, Edaravone 参考 参考 Katare, R. G., et al. 2003. Am. J. Physiol. 285, H2171.
Kawai, H., et al. 1997. J. Pharmacol. Exp. Ther. 281, 921.
Yamamoto, Y., et al. 1996. Redox. Report 2, 333.
Watanabe, T., et al. 1994. J. Pharmacol. Exp. Ther. 268, 1597.
Nishi, H., et al. 1989. Stroke 20, 1236.产品信息 CAS号 89-25-8 具有ATP竞争性 N 形式 Cream-colored solid Hill配方 C₁₀H₁₀N₂O 化学配方 C₁₀H₁₀N₂O Molar Mass 174.2 可逆 N 结构配方图像 生物信息 主靶 A free radical scavenger and antioxidant 主靶IC50 15 µM inhibiting iron-dependent peroxidation in rat brain homogenates 纯度 ≥98% by HPLC 理化信息 细胞可渗透 N 溶解度 DMSO GHS安全信息 RTECS UQ9625000 安全信息 R相 R: 22-36/37/38-43
Harmful if swallowed.
Irritating to eyes, respiratory system and skin.
May cause sensitization by skin contact.S相 S: 26-36
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing.储存和货运信息 货运代码 Ambient Temperature Only
毒性 Harmful
储存 +2°C to +8°C
避光 Protect from light
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. 包装信息 惰性气体下包装 Packaged under inert gas
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