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品种反应性 主要应用 宿主 格式 抗体类型 M WB M Purified Monoclonal Antibody 描述 产品目录编号 MABS193 描述 Anti-v-Src Antibody, clone 327 Alternate Names - p60-Src
- Proto-oncogene tyrosine-protein kinase Src
- Proto-oncogene c-Src
- pp60c-src
背景信息 v-Src is the product of the Rous sarcoma virus (RSV) oncogene, and functions as a non-receptor tyrosine kinase belonging to the family of Src proteins. Srcs are typically activated by dimerized cell surface receptors such as integrins, receptor tyrosine kinases, and cytokine receptors. Activated Src kinases phosphorylate the cytoplasmic domains of these receptors enabling interaction between these receptors and their downstream effector molecules. Src proteins are involved in many cellular processs such as apoptosis, immunity, gene expression, cell adhesion, cell migration, and cell transformation. Previous studies have reported that v-Src plays an important role in tumorigenesis. 产品信息 格式 Purified 控制 - NIH/3T3 cell lysate
演示 Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Anti-v-Src Antibody, clone 327 detects level of v-Src & has been published & validated for use in Western Blotting. 主要应用 - Western Blotting
生物信息 免疫原品种 Recombinant protein corresponding to purified pp60src from bacterial recombinants which direct the synthesis of v-Src. 克隆 327 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Mouse 同种型 IgG1κ 品种反应性 Mouse 抗体类型 Monoclonal Antibody Entrez基因编号 - NP_005408
基因符号 - SRC1
- SRC
纯化方法 Protein G purified UniProt编号 - P12931
产品使用声明 质量保证 Evaluated by Western Blot in NIH/3T3 cell lysate.
Western Blot Analysis: 0.1 µg/mL of this antibody detected v-Src in 10 µg of NIH/3T3 cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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