merck millipore,默克密理博,MABS390,Anti-FABP2 Antibody, clone EPR7136, rabbit monoclonal

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merck millipore,默克密理博,MABS390,Anti-FABP2 Antibody, clone EPR7136, rabbit monoclonal
产品名称：Anti-FABP2 Antibody, clone EPR7136, rabbit monoclonal
产品型号：MABS390
Please note that this product will not be available for sale after March 15, 2015. Please select one of the other antibodies against this target. Detect Fatty Acid Binding Protein using this rabbit More>>

merck millipore,默克密理博,MABS390,Anti-FABP2 Antibody, clone EPR7136, rabbit monoclonal

产品介绍

merck millipore,默克密理博,MABS390,Anti-FABP2 Antibody, clone EPR7136, rabbit monoclonal

重要规格表

品种反应性	主要应用	宿主	格式	抗体类型
R, H, M	WB	Rb	Unpurified	Monoclonal Antibody

描述
产品目录编号	MABS390
描述	Anti-FABP2 Antibody, clone EPR7136, rabbit monoclonal
Alternate Names	I-FABP Fatty acid-binding protein, intestinal Fatty acid-binding protein 2 Intestinal-type fatty acid-binding protein
背景信息	Fatty acid-binding protein 2, (FABP2) is a fatty acid-binding protein produced by the intestinal tissues of the small intestine and participates in the transport and intracellular internalization and metabolism of fatty acids in the gut. Its expression is localized to the small intestine, especially within the cellular epithelial cells of the jejunum, with much lower levels in the large intestine. Its expression is confined to the cytoplasm and induced by growth factors such as EGF. FABP2 is also known as FABPI or I-FABP. Because of its role in fatty acid uptake and lipid homeostasis, mutations or polymorphisms affecting the function of FABP2 in fatty acid metabolism have been a source of recent research. In particular, an amino acid substitution known as A54T where the G to A polymorphism of codon 54 of the FABP2 gene results in the substation of a Thr in the mutated form instead of an Ala in the normal form. This Thr-codon 54 mutation demonstrates an increased affinity for long-chain fatty acids and is strongly associated with factors associated with metabolic syndrome disease, including insulin resistance, enhanced fatty acid oxidation, elevated triglycerides and type 2 diabetes. Furthermore, FABPs and in particular , FABP2, play an increasingly important role in controlling the lipid signaling cascade and FABP2 is being studied as key regulatory factor of lipid signaling under normal and pathological conditions. EMD-Millipore’s Anti-FABP2 rabbit monoclonal antibody has been tested in western blot on human, rat and mouse small intestine tissue lysates.

产品信息
格式	Unpurified
控制	Human small intestine, rat small intestine, and mouse small intestine tissue lysates
演示	Rabbit monoclonal in buffer containing PBS with up to 0.1% sodium azide, 0.05% BSA, and 50% glycerol.

应用
应用	Please note that this product will not be available for sale after March 15, 2015. Please select one of the other antibodies against this target. Detect Fatty Acid Binding Protein using this rabbit monoclonal antibody, Anti-FABP2 Antibody & clone EPR7136 validated for use in western blotting.
主要应用	Western Blotting

生物信息
免疫原品种	Synthetic peptide corresponding to human FABP2.
克隆	EPR7136
宿主	Rabbit
品种反应性	RatHumanMouse
抗体类型	Monoclonal Antibody
基因符号	FABPI FABP2
纯化方法	Unpurified
UniProt编号	P12104

产品使用声明
质量保证	Evaluated by Western Blotting in human small intestine, rat small intestine, and mouse small intestine tissue lysates. Western Blotting Analysis: A 1:1,000-10,000 dilution of this antibody detected FABP2 in human small intestine, rat small intestine, and mouse small intestine tissue lysates. Optimal working dilutions must be determined by end user.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.

储存和货运信息

存储条件

Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.