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重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 R, H WB, ELISA, ICC Rb Purified Polyclonal Antibody 描述 产品目录编号 AB3279 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-Hexokinase Type II Antibody Alternate Names - HK II
产品信息 格式 Purified 控制 - insulin-responsive tissues such as skeletal muscle
演示 Liquid. Partially Purified rabbit Serum. Antibodies reactive with the Type I isozyme were present in the original antiSerum; these were removed by affinity chromatography on a column of immobilized Type I isozyme, and the affinity-depleted Serum restored to original volume. 应用 应用 Anti-Hexokinase Type II Antibody is an antibody against Hexokinase Type II for use in ELISA, IC & WB. 主要应用 - Western Blotting
- ELISA
- Immunocytochemistry
应用说明 Western Blot: 1:5,000-1:10,000.
Immunocytochemistry using indirect immunofluorescence.
ELISA
Optimal working dilutions must be determined by the end user.生物信息 免疫原品种 Recombinant rat Type II hexokinase. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 Reacts with the Type II isozyme of rat hexokinase (102 kDa). No reactivity with the Type I or Type III isozymes of rat hexokinase by immunoblot or ELISA. Reactivity with human and hamster Type II isozyme has been confirmed by immunoblotting, and reactivity with Type II isozyme from other mammalian species is expected. 品种反应性 RatHuman 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_000189.4
Entrez基因汇总 Hexokinases phosphorylate glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells. 基因符号 - EC 2.7.1.1
- HK2
- HKII
- Hexokinase-2
- HXK2
- DKFZp686M1669
纯化方法 Immunodepleted Serum UniProt编号 - P52789
UniProt汇总 SIZE: 917 amino acids; 102380 Da
SUBUNIT: Monomer (By similarity).
SUBCELLULAR LOCATION: Mitochondrion outer membrane (By similarity). Note=Its hydrophobic N-terminal sequence may be involved in membrane binding (By similarity).
TISSUE SPECIFICITY: Predominant hexokinase isozyme expressed in insulin-responsive tissues such as skeletal muscle.
DOMAIN: SwissProt: P52789 The N- and C-terminal halves of this hexokinase show extensive sequence similarity to each other. The catalytic activity is associated with the C-terminus while regulatory function is associated with the N-terminus.
SIMILARITY: Belongs to the hexokinase family.
MISCELLANEOUS: In vertebrates there are four major glucose- phosphorylating isoenzymes, designated hexokinase I, II, III and IV (glucokinase).产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. 包装信息 数量 100 µL
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