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品种反应性 主要应用 宿主 格式 抗体类型 H WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABT52 描述 Anti-phospho-Peak Antibody (Tyr665) Alternate Names - Tyrosine-protein kinase SgK269
- Pseudopodium-enriched atypical kinase 1
- Sugen kinase 269
背景信息 Pseudopodium-enriched atypical kinase 1 (Peak1; KIAA2002, or sgk269) is a ubiquitous non-receptor tyrosine kinase that belongs to the NFK3 family. It interacts with actin filaments via its N-terminal actin-targeting region. It also modulates the activity of multiple cytoskeletal regulatory proteins such as paxillin, p130Cas, Erk, and Crk; and mediates cell proliferation and migration via the Ras/Raf/Erk and Src-p130Cas-Crk-Paxillin pathways. Peak1 may play an important role in the progression of tumors. 产品信息 格式 Affinity Purified 控制 - Modified and non modified peptides of phosphorylated and non-phosphorlyated Peak proteins
演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 This phospho-Peak antibody is validated for use in WB & Dot Blot for the detection of the phospho-Peak protein. 主要应用 - Western Blotting
应用说明 Western Blot Analysis: A representative lot was used by an independent laboratory in 293T cells transfected with wildtype GFP-Peak. (Dr. Richard Klemke, University of California-San Diego.) 生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to human Peak phosphorylated at Tyr665. 表位 Phosphorylated Tyr665 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 This antibody recognizes Peak phosphorylated at Tyr665. 品种反应性 Human Species Reactivity Note Demonstrated to react with Human. Predicted to react with Rat, Porcine, Sumatran Orangutan, and Mouse based on 100% sequence homology. 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_079052
基因符号 - PEAK1
纯化方法 Affinity purified UniProt编号 - Q9H792
产品使用声明 质量保证 Evaluated by Dot Blot in modified and non modified peptides of phosphorylated and non-phosphorlyated Peak proteins.
Dot Blot (Specificity) Analysis: A representative lot blocked phospho-Peak (Tyr665) in modified and non modified peptides of phosphorylated and non-phosphorlyated Peak proteins.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
上一件merck millipore产品：merck millipore,默克密理博,IL007,Interleukin-7 Protein, Recombinant human
下一件merck millipore产品：merck millipore,默克密理博,04-1027,Anti-SGK Antibody, clone Y238, rabbit monoclonal
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