- 当前位置：首页 > >Merck Millipore > 生命科学研究
- 生命科学研究
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 R, H, M WB Rb Purified Polyclonal Antibody 描述 产品目录编号 07-091 品牌系列 Upstate
商名 - Upstate
描述 Anti-Pin1 Antibody 背景信息 Pin1 is a peptidyl-prolyl isomerase (PPI) that targets phosphorylated Ser or Thr residues followed by a Pro (S/T-P). Isomerization of phosphorylated Ser or Thr residues may alter protein confirmation and, subsequently, modify activity. Pin1 is overexpressed in many human breast cancers, and has been shown to modify numerous proteins including p53,
NF-κB, c-Jun, cyclin D1, and β-catenin.产品信息 格式 Purified 控制 - 3T3 cell lysate, HeLa cell lysate, MCF-7 cell lysate
演示 Presentation: 100 µg of protein A purified rabbit IgG in 100 µL of 0.014 M phosphate buffer, pH 7.6, 0.175 M NaCl, 0.07% Sodium Azide and 30% glycerol. Liquid at -20°C. 应用 应用 Anti-Pin1 Antibody is a high quality Rabbit Polyclonal Antibody for the detection of Pin1 & has been validated in IP & WB. 主要应用 - Western Blotting
生物信息 免疫原品种 Full-length His tagged human Pin-1 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 Pin1 同种型 IgG 品种反应性 RatHumanMouse 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_006221
基因符号 - DOD
- PIN1
- dod
- UBL5
纯化方法 Protein A chromatography UniProt编号 - Q13526
UniProt汇总 FUNCTION: SwissProt: Q13526 # Essential PPIase that regulates mitosis presumably by interacting with NIMA and attenuating its mitosis-promoting activity. Displays a preference for an acidic residue N-terminal to the isomerized proline bond. Catalyzing pSer/Thr-Pro cis/trans isomerizations.
SIZE: 163 amino acids; 18243 Da
SUBUNIT: Interacts with STIL (By similarity). Interacts with MPHOSPH1.
SUBCELLULAR LOCATION: Nucleus.
DOMAIN:SwissProt: Q13526 The WW domain is required for the interaction with STIL and MPHOSPH1.
PTM: Phosphorylated upon DNA damage, probably by ATM or ATR.
SIMILARITY: Contains 1 PpiC domain. & Contains 1 WW domain.产品使用声明 质量保证 Routinely evaluated by immunoblot on RIPA lysates from mouse 3T3/A31 cells 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 2 years at -20°C 包装信息 数量 100 µg
上一件merck millipore产品：merck millipore,默克密理博,AB3279,Anti-Hexokinase Type II Antibody
下一件merck millipore产品：merck millipore,默克密理博,14-610M,Flt-3 (D835Y) Protein, active, 250 µg
相关产品
merck millipore,默克密理博,04-1027,Anti-SGK Antibody, clone Y238, rabbit monoclonal
merck millipore,默克密理博,506148,InSolution™ p38 MAP Kinase Inhibitor III - Calbiochem
merck millipore,默克密理博,MABS390,Anti-FABP2 Antibody, clone EPR7136, rabbit monoclonal
merck millipore,默克密理博,AB6008,Anti-MMP-9 Antibody, Hinge region
merck millipore,默克密理博,AB3279,Anti-Hexokinase Type II Antibody
merck millipore,默克密理博,14-610M,Flt-3 (D835Y) Protein, active, 250 µg
merck millipore,默克密理博,ECM200,QCM 3 µm Endothelial Cell Migration Assay Fibronectin, Colorimetric
merck millipore,默克密理博,ST1602,Anti-APLN Mouse mAb (2A1-2D5)
merck millipore,默克密理博,207007,Calcineurin Cellular Activity Assay Kit, Colorimetric