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merck millipore,默克密理博,MABS192,Anti-IGF-IR Antibody, clone αIR3 (Azide Free)
产品名称：Anti-IGF-IR Antibody, clone αIR3 (Azide Free)
产品型号：MABS192
Anti-IGF-IR Antibody, clone αIR3 (Azide Free) is an antibody against IGF-IR for use in ICC.
merck millipore,默克密理博,MABS192,Anti-IGF-IR Antibody, clone αIR3 (Azide Free)
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H ICC M Purified Monoclonal Antibody 描述 产品目录编号 MABS192 描述 Anti-IGF-IR Antibody, clone αIR3 (Azide Free) Alternate Names - CD221
- Insulin-like growth factor 1 receptor
- Insulin-like growth factor I receptor
- IGF-I receptor
背景信息 The insulin-like growth factors (IGFs) or somatomedins are mitogenic peptides present in the plasma of human, rat, and other species. Two distinct but chemically related IGFs have been purified from human plasma: IGF-I (Somatomedin C) and IGF-II. They are single chain polypeptides with molecular weights of 7,640 and 7,471, respectively. Types I and II IGF receptors differ in their structure and in their peptide binding specificity. Type I IGF receptors are structurally homologous to insulin receptors and contain alpha-subunits (MW = 130,000) that bind peptide, and beta-subunits (MW = 90,000), which have intrinsic tyrosine kinase activity. The protein-tyrosine kinase activity of the insulin receptor and, presumably the IGF-I receptor, is required for insulin to stimulate all of its biological responses in cells. MABS192 is constituted as azide-free. 产品信息 格式 Purified 控制 - HepG2 cells
演示 Purified mouse monoclonal IgG1κ in buffer containing PBS without preservatives. 应用 应用 Anti-IGF-IR Antibody, clone αIR3 (Azide Free) is an antibody against IGF-IR for use in ICC. 主要应用 - Immunocytochemistry
应用说明 Neutralization Assay Analysis: A representative lot detected IGF-IR in NEUT (Rohlik, Q. T., et al. (1987). Biochem Biophys Res Commun. 149(1):276-281; Kull, F. C. Jr., et al. (1983). 258(10):6561-6566.). 生物信息 免疫原品种 Partially purified human placenta IGF-1 receptor 克隆 αIR3 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Mouse 同种型 IgG1κ 品种反应性 Human Species Reactivity Note Demonstrated to react with Human. 抗体类型 Monoclonal Antibody Entrez基因编号 - NP_000866
基因符号 - IGF1R
纯化方法 Protein G purified UniProt编号 - P08069
产品使用声明 质量保证 Immunocytochemistry Analysis: A 1:500 dilution of this antibody detected IGF-IR in HepG2 cells. 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.包装信息 数量 100 µL
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