merck millipore,默克密理博,AB9306,Anti-NAP-22 Antibody, effector domain

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Merck Millipore 默克密理愽

品种反应性	主要应用	宿主	格式	抗体类型
R, H, M	WB	Rb	Purified	Polyclonal Antibody

描述
产品目录编号	AB9306
品牌系列	Chemicon®
商名	Chemicon
描述	Anti-NAP-22 Antibody, effector domain
Alternate Names	Neuronal acidic protein 22, CAP-23, BASP1 Neuronal acidic protein 22 CAP-23
背景信息	NAP-22, a member of the BASP-1 family of proteins, is a membrane-anchored protein that is associated with neuronal growth cones at the tips of elongating axons. In addition to nervous tissues, it is also expressed in testes, kidney, and lymphoid organs. NAP-22 is myristoylated at its N-terminal glycine residue imparting both hydrophobic and hydrophilic properties to the protein. While the mass of NAP-22 has been determined to be 22.78 kDa by mass spectrometry, it demonstrates an anomalously high molecular weight by SDS-PAGE (~ 55 kDa).

产品信息
格式	Purified
控制	POSITIVE CONTROL: Neonatal rat brain extract. NAP-22 is heat and acid resistant. Heat or acid-treated supernatants from crude tissue or cell homogenates are good sources to analyze NAP-22 content by immunoblot.
演示	Semi-purified immunoglobulin. Liquid in TBS containing 0.05% sodium azide.

应用
应用	Detect NAP-22 using this Anti-NAP-22 Antibody, effector domain validated for use in WB.
主要应用	Western Blotting
应用说明	Immunoblotting: 1:1,000 using rat brain extract (colormetric; higher dilutions may be used with ECL). The antibody reacts with the 55 kDa NAP-22 protein. The suggested dilution buffer is TBS containing 0.05% Tween-20. Suggested blocking buffer is 5% non-fat dry milk. Suggested transfer membrane is PVDF-Immobilon. Suggested gel percentage is 10%. Overnight incubation with the antibody is recommended. Optimal working dilutions must be determined by the end user.

生物信息
免疫原品种	Synthetic peptide from mouse NAP-22, effector domain.
表位	Effector domain
宿主	Rabbit
特异性	Recognizes NAP-22 effector domain.
品种反应性	RatHumanMouse
抗体类型	Polyclonal Antibody
Entrez基因编号	NM_006317.3
Entrez基因汇总	This gene encodes a membrane bound protein with several transient phosphorylation sites and PEST motifs. Conservation of proteins with PEST sequences among different species supports their functional significance. PEST sequences typically occur in proteins with high turnover rates. Immunological characteristics of this protein are species specific. This protein also undergoes N-terminal myristoylation.
基因符号	CAP23 BASP1 CAP-23 NAP22 MGC8555 NAP-22
UniProt编号	P80723
UniProt汇总	SIZE: 227 amino acids; 22693 Da SUBCELLULAR LOCATION: Membrane; Lipid-anchor. Cell projection, growth cone. Note=Associated with the membranes of growth cones that form the tips of elongating axons. TISSUE SPECIFICITY: Brain. SIMILARITY: SwissProt: P80723 ## Belongs to the BASP/NAP22 family.

产品使用声明
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.

包装信息
数量	50 µL

merck millipore,默克密理博,AB9306,Anti-NAP-22 Antibody, effector domain

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