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品种反应性 主要应用 宿主 格式 抗体类型 M WB M Purified Monoclonal Antibody 描述 产品目录编号 MAB4356 描述 Anti-DPPA-2 Antibody, clone 6C1.2 Alternate Names - developmental pluripotency associated 2
- Pluripotent embryonic stem cell-related gene 1 protein
背景信息 DPPA-2 (developmental pluripotency associated-2) is a novel Oct-4-related protein that is localized to the nucleus of mouse fetal germ cells. DPPA-2 has binding sites for both POU and Sox-2 protein domains and is expressed primarily in the developing germ line following gastrulation. These associations suggest that this protein participates in a very strong supportive role in maintaining cell pluripotentiality. In addition to its role as a pluripotency marker, more recent research using cancer cells suggests that DPPA-2 may also act as an embryo-cancer antigen—pointing to the presence of abnormal cell growth and the formation of cancerous cells. 产品信息 格式 Purified 演示 Purified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4) and
150 mM NaCl with 0.05% sodium azide.应用 应用 This Anti-DPPA-2 Antibody, clone 6C1.2 is validated for use in WB for the detection of DPPA-2. 主要应用 - Western Blotting
生物信息 免疫原品种 Full length recombinant mouse DPPA-2 protein. 克隆 6C1.2 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Mouse 特异性 This monoclonal antibody recognizes the mouse DPPA-2 protein. 同种型 IgG2aκ 品种反应性 Mouse Species Reactivity Note Reacts with mouse. Reactivity with other species has not been tested. 抗体类型 Monoclonal Antibody Entrez基因编号 - Q9CWH0
基因符号 - PESCRG1
纯化方法 Protein G purfied UniProt编号 - Q7Z7J5
UniProt汇总 FUNCTION: May play a role in maintaining cell pluripotentiality.
SUBCELLULAR LOCATION: Nucleus.
TISSUE SPECIFICITY: Expressed in embryonic stem cells. No expression is seen in 5 months embryo, mesenchymal stem cells, embryonic fibrocytes and adult tissues.
SEQUENCE SIMILARITIES: Contains 1 SAP domain.产品使用声明 质量保证 (Based upon representative data from a previous lot).
Western Blotting: Recommended working concentration is 2 µg/mL.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain refrigerated at 2-8°C in undiluted aliquots for up to 12 months. 包装信息 数量 100 µg
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