merck millipore,默克密理愽
  • merck millipore,默克密理博,MABN721,Anti-PTK7 Antibody, clone 4F9

  • merck millipore,默克密理博,MABN721,Anti-PTK7 Antibody, clone 4F9

    产品名称：Anti-PTK7 Antibody, clone 4F9
    产品型号：MABN721
    Detect Protein-tyrosine kinase 7 using this mouse monoclonal antibody, Anti-PTK7 Antibody, clone 4F9 validated for use in western blotting & IHC.

    merck millipore,默克密理博,MABN721,Anti-PTK7 Antibody, clone 4F9

  • 产品介绍
  • merck millipore,默克密理博,MABN721,Anti-PTK7 Antibody, clone 4F9

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    HIHC, WBMAscitesMonoclonal Antibody
    描述
    产品目录编号 MABN721
    描述 Anti-PTK7 Antibody, clone 4F9
    Alternate Names
    • Tyrosine-protein kinase-like 7
    • Inactive tyrosine-protein kinase 7
    • CCK-4
    • Protein-tyrosine kinase 7
    • Pseudo tyrosine kinase receptor 7
    背景信息 The gene PTK7 encodes the protein named Inactive tyrosine-protein kinase 7 or Protein-tyrosine kinase 7, or colon carcinoma kinase 4 (CCK4). The PTK7 encoded protein is an interesting single pass type 1 membrane protein involved in Wnt signaling. It is interesting because it contains an inactive tyrosine kinase domain yet it is a component of both the canonical Wnt and non-canonical signaling pathways, and operates during embryogenesis and angiogenesis. Moreover, the PTK7 protein functions in cell migration, cell adhesion, cell polarity, cytoskeleton reorganization and apoptosis, and the PTK7 encoded protein co-localizes with MMP14 at cell junctions as well as the leading edge of migrating cells. The PTK7 encoded protein is expressed in lung, liver, pancreas and other tissues like kidney, placenta and melanocytes. The PTK7 encoded protein does not seem to be expressed in colon and has low expression in brain, heart, and skeletal muscle. EMD-Millipore’s Anti-PTK7 mouse monoclonal, clone 4F9 has been tested by western blot against multiple human cancer cells lines and in immunohistochemistry using paraffin-embedded human lung cancer tissue with DAB detection.
    产品信息
    格式 Ascites
    控制
    • A431 cell lysate
    演示 Mouse monoclonal IgG2b ascitic fluid containing up to 0.1% sodium azide.
    应用
    应用 Detect Protein-tyrosine kinase 7 using this mouse monoclonal antibody, Anti-PTK7 Antibody, clone 4F9 validated for use in western blotting & IHC.
    主要应用
    • Immunohistochemistry
    • Western Blotting
    应用说明 Immunohistochemistry Analysis: A 1:100 and 1:500 dilution from a representative lot detected PTK7 in human lung and kidney tissues.
    生物信息
    免疫原品种 Purified protein fragment of human PTK7 expressed in E. coli.
    克隆 4F9
    宿主 Mouse
    同种型 IgG1
    品种反应性 Human
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NP_002812
    基因符号
    • PTK7
    • CCK4
    纯化方法 Unpurified
    UniProt编号
    • Q13308
    产品使用声明
    质量保证 Evaluated by Western Blotting in A431 cell lysate.

    Western Blotting Analysis:A 1:1,000 dilution of this antibody detected PTK7 in 10 µg of A431 cell lysate.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 1 year at -20°C from date of receipt.
    Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
    包装信息
    数量 100 µL

    merck millipore,默克密理博,MABN721,Anti-PTK7 Antibody, clone 4F9

上一件merck millipore产品：merck millipore,默克密理博,382115,Histone Acetyl Transferase Inhibitor VII, CTK7A - Calbiochem
下一件merck millipore产品：merck millipore,默克密理博,FCMAB423PE,Milli-Mark Anti-HDAC2-PE Antibody, clone 3F3


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