merck millipore,默克密理愽
  • merck millipore,默克密理博,203695,bpV(phen) - CAS 42494-73-5 - Calbiochem

  • merck millipore,默克密理博,203695,bpV(phen) - CAS 42494-73-5 - Calbiochem

    产品名称：bpV(phen) - CAS 42494-73-5 - Calbiochem
    产品型号：203695
    A potent protein phosphotyrosine phosphatase inhibitor and insulin receptor kinase (IRK) activator.

    merck millipore,默克密理博,203695,bpV(phen) - CAS 42494-73-5 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,203695,bpV(phen) - CAS 42494-73-5 - Calbiochem

    重要规格表

    经验配方 CAS号
    K[VO(O₂)₂C₁₂H₈N₂]42494-73-5
    描述
    概述 A potent protein phosphotyrosine phosphatase inhibitor and insulin receptor kinase (IRK) activator. Excellent insulin mimetic at 15 µg/kg in vitro and in vivo for use. Inhibits the in situ dephosphorylation of autophosphorylated insulin receptors with over 1000-fold greater potency than sodium orthovanadate. Arrests proliferation of neuroblastoma NB 41 and glioma C6 cells at the G2/M transition of the cell cycle. Also reported to potently inhibit PTEN (IC50 = 38 nM).
    The water content varies from lot to lot and is supplied on the label along with the lot-specific molecular weight.
    产品目录编号 203695
    品牌系列 Calbiochem®
    同义词 Potassium Bisperoxo(1,10-phenanthroline)oxovanadate (V), PTEN Inhibitor I, PTP Inhibitor VIII
    参考
    参考 Schmid, A.C., et al. 2004. FEBS Lett. 566, 35.
    Muzyamba, M.C., et al. 1999. J. Physiol. 517, 421.
    Drake, P.G., et al. 1996. Endocrinology 137, 4960.
    Bevan, A.P., et al. 1995. Am. J. Physiol. 268, E60.
    Bevan, A.P., et al. 1995. J. Biol. Chem. 270, 10784.
    Yale, J.F., et al. 1995. Diabetes 44, 1274.
    Posner, B.I., et al. 1994. J. Biol. Chem. 269, 4596.
    产品信息
    CAS号 42494-73-5
    具有ATP竞争性 N
    形式 Yellow solid
    Hill配方 K[VO(O₂)₂C₁₂H₈N₂]
    化学配方 K[VO(O₂)₂C₁₂H₈N₂]
    Molar Mass 350.2
    可逆 N
    结构配方图像
    生物信息
    主靶 PTEN
    主靶IC50 38 nM
    纯度 ≥99% by ⁵¹V-NMR
    理化信息
    细胞可渗透 N
    溶解度 H₂O
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 -20°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Unstable in solution; reconstitute just prior to use.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,203695,bpV(phen) - CAS 42494-73-5 - Calbiochem

上一件merck millipore产品：merck millipore,默克密理博,ABN351,Anti-LGI3 Antibody
下一件merck millipore产品：merck millipore,默克密理博,382115,Histone Acetyl Transferase Inhibitor VII, CTK7A - Calbiochem


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