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品种反应性 主要应用 宿主 格式 抗体类型 H WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABN351 描述 Anti-LGI3 Antibody Alternate Names - LGI3
- Leucine-rich repeat LGI family member 3
- LGI1-like protein 4
- Leucine-rich glioma-inactivated protein 3
背景信息 The leucine-rich, glioma inactivated gene 3 (LGI3) is a member of the LGI family in which LGI1 is the exemplar. The LGI family consists of four of highly related proteins containing leucine-rich repeats (LRRs) which are highly similar to other transmembrane signaling molecules and receptors. LGI1 has been identified as a candidate tumor suppressor gene for glioma and plays a role in autodominant lateral temporal epilepsy (ADTLE), an epileptic syndrome characterized by focal seizures with predominant auditory symptoms. Despite its high homology with LGI1 and similar pattern of expression, mutations in LGI3 have not been found to be associated with ADTLE. LGI3 expression is induced in rat astrocyte cultures by the amyloid beta (Abeta) peptide and accumulated on neuronal plasma membranes of aged monkey brains and co-localized with Abeta. 产品信息 格式 Affinity Purified 控制 - Human brain tissue lysate
演示 Purified rabbit polyclonal in buffer containing PBS with 0.02% sodium azide. 应用 应用 Detect the LGI3 protein using this Anti-LGI3 validated for use in WB. 主要应用 - Western Blotting
生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to human LGI3. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 Two isoforms of LGI3 are known to exist; this LGI3 antibody will recognize both. 品种反应性 Human 抗体类型 Polyclonal Antibody 基因符号 - LGIL4
- LGI3
纯化方法 Antigen Affinity purified UniProt编号 - Q8N145
产品使用声明 质量保证 Evaluated by Western Blot in human brain tissue lysate.
Western Blot Analysis: 2 µg/mL of this antibody detected LGI3 in 15 µg of human brain tissue lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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