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品种反应性 主要应用 宿主 格式 抗体类型 M WB R Purified Monoclonal Antibody 描述 产品目录编号 MABF34 描述 Anti-Thy-1 Antibody, clone M5/49 Alternate Names - CD90 antigen
- Thy-1 cell surface antigen
- Thy-1 T-cell antigen
- Thy-1 membrane glycoprotein
- Thy-1 antigen
背景信息 Thy-1 membrane glycoprotein (Thy-1) is a glycosylphosphatidylinositol (GPI)-anchored surface protein belonging to the immunoglobulin superfamily and is a major cell surface protein found on both T–cells and in the brain. Thy-1 is thought to be involved in interactions taking place during synaptogenesis and other neurological events between cells or cells and their ligands. There are two known alleles for Thy-1; Thy1.1 and Thy1.2. Studies have shown N-glycosolation to take place at three locations on the protein. 产品信息 格式 Purified 控制 - P388D1 cell lysate
演示 Purified rat monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Anti-Thy-1 Antibody, clone M5/49 detects level of Thy-1 & has been published & validated for use in WB. 主要应用 - Western Blotting
应用说明 Functional Assay: A previous lot of this antibody was used for the inhibition of B6 Anti-BNLΦ CTL mediated cell death. (Davignon, D., et al. (1981). PNAS USA. 78(7):4535-4539.) 生物信息 免疫原品种 B6 Anti-BNL4Φ lymphocytes 克隆 M549.4.1 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rat 同种型 IgG2aκ 品种反应性 Mouse Species Reactivity Note Demonstrated to react with mouse. 抗体类型 Monoclonal Antibody Entrez基因编号 - NP_033408
基因符号 - CDw90
- THY1
- CD90
- Thy-1
纯化方法 Protein G Purified UniProt编号 - P01831
UniProt汇总 FUNCTION: May play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain.
SUBCELLULAR LOCATION: Cell membrane; Lipid-anchor › GPI-anchor
POLYMORPHISM: There are two major alleles; Thy-1.1 (CD90.1) and Thy-1.2 (CD90.2).
SEQUENCE SIMILARITIES: Contains 1 Ig-like V-type (immunoglobulin-like) domain.产品使用声明 质量保证 Evaluated by Western Blot in P388D1 cell lysate.
Western Blot Analysis: 0.5 µg/mL of this antibody detected Thy-1 in 10 µg of P388D1 cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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