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品种反应性 主要应用 宿主 格式 抗体类型 R, M, H IHC, WB M Purified Monoclonal Antibody 描述 产品目录编号 MABN497 描述 Anti-PSD93 Antibody, clone N18/30 Alternate Names - Postsynaptic density protein PSD-93
- Disks large homolog 2
- Channel-associated protein of synapse-110
- Chapsyn-110
背景信息 As a member of the membrane-associated guanylate kinase (MAGUK) family, PSD93 (also known as Chapsyn-110) binds directly to the N-methyl-D-aspartate (NMDA) receptor and the Shaker K+ channel subunits. It shares 70-80% homology with PSD-95 (SAP90), and SAP97. Like PSD-95, PSD93 plays a key role in postsynaptic targeting. Aside from binding to glutamate receptors, the MAGUK family of proteins also interacts with cell surface structures, like cell adhesion molecules, ion channels, cytoskeletal elements, and signal transduction molecules. Improper PSD93 signaling has been implicated in certain disease states, such as schizophrenia. 产品信息 格式 Purified 控制 - Mouse brain tissue lysate
演示 Purified mouse monoclonal IgG1 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Detect PSD93 using this Anti-PSD93 Antibody, clone N18/30 validated for use in Western Blotting & IHC. 主要应用 - Immunohistochemistry
- Western Blotting
应用说明 Western Blot Analysis: 1 µg/mL from a representative lot detected PSD93 in 10 µg of human brain tissue lysate.
Immunohistochemistry Analysis: A representative lot detected PSD93 in rat brain tissue (Prof. J. Trimmer, University of California, Davis).
Western Blot Analyis: A representative lot detected PSD93 in WT, but not in PSD93 knockout mice.
Western Blot Analysis: A representative lot detected PSD93 in CA1 tissue lysates from C57BL/6 mice (Jeffrey, R. A., et al. (2009). J Neurosci. 29(50):15613-15620.).生物信息 免疫原品种 Recombinant protein corresponding to rat PSD93. 克隆 N18/30 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Mouse 同种型 IgG1κ 品种反应性 RatMouseHuman Species Reactivity Note Demonstrated to react with Mouse, Human, and Rat. This antibody does not demonstrate cross reactivity with other MAGUK family members, such as PSD-95, SAP97, and SAP102 expressed in transfected cells. 抗体类型 Monoclonal Antibody Entrez基因编号 - NP_071618
基因符号 - Dlgh2
- Dlg2
纯化方法 Protein G purified UniProt编号 - Q63622
产品使用声明 质量保证 Evaluated by Western Blot in mouse brain tissue lysate.
Western Blot Analysis: 1 µg/mL of this antibody detected PSD93 in 10 µg of mouse brain tissue lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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下一件merck millipore产品：merck millipore,默克密理博,07-1562,Anti-EZH2 Antibody
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