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merck millipore,默克密理博,MABN481,Anti-Lipocalin-2 Antibody, clone PA348-26.3.5
产品名称:Anti-Lipocalin-2 Antibody, clone PA348-26.3.5
产品型号:MABN481
Detect Lipocalin using this mouse monoclonal antibody, Anti-Lipocalin-2 Antibody, clone PA348-26.3.5 validated for use in western blotting, IHC & ELISA.
merck millipore,默克密理博,MABN481,Anti-Lipocalin-2 Antibody, clone PA348-26.3.5
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H ELISA, WB, IHC M Purified Monoclonal Antibody 描述 产品目录编号 MABN481 描述 Anti-Lipocalin-2 Antibody, clone PA348-26.3.5 Alternate Names - p25
- ngal
- neutrophil lipocalin
- siderocalin
- Neutrophil gelatinase-associated lipocalin
- NGAL
- 25 kDa alpha-2-microglobulin-related subunit of MMP-9
- Lipocalin-2
- Oncogene 24p3
- Siderocalin LCN2
背景信息 Lipocalin-2 (LCN2) (also known as Neurophil Gelatinase-Associated Lipocalin or NGAL) belongs to a superfamily of lipocalins, a collection of small, diversely functional, extracellular proteins. Lipocalin-2 is secreted from neutrophil granules in three different forms: a monomer of 25 kDa, a disulfide-linked homodimer at 46 kDa, and a disulfide-linked heterodimer with MMP-9 at 135-kDa. It is widely known to induce development of kidney epithelia, to bind and traffic iron, and to act as a molecular signal under inflammatory conditions, such as Crohn’s Disease. Multiple carcinoma studies have also shown elevated expression levels of Lipocalin-2 in several different human tumors affecting such organs as colon, lung, breast, ovaries, and pancreas. Additionally, there has been great interest in this protein as a possible marker for onset of Acute Kidney Injury following cardiac surgery, the progression of Chronic Kidney Disease (CKD), and the survival chances of patients with Chronic Heart Failure (CHF). 产品信息 格式 Purified 演示 Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Detect Lipocalin using this mouse monoclonal antibody, Anti-Lipocalin-2 Antibody, clone PA348-26.3.5 validated for use in western blotting, IHC & ELISA. 主要应用 - ELISA
- Western Blotting
- Immunohistochemistry
应用说明 Immunohistochemistry Analysis: A 1:2,000 dilution from a representative lot detected Lipoacalin-2 in human bone marrow and stomach tissue lysate.
ELISA Analysis: A representative lot from an independent laboratory detected Lipocalin-2 in indirect ELISA.生物信息 免疫原品种 Recombinant protein corresponding to human Lipocalin-2. 克隆 PA348-26.3.5 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Mouse 同种型 IgG1κ 品种反应性 Human 抗体类型 Monoclonal Antibody Entrez基因编号 - NP_005555.1
基因符号 - NGAL
- LCN2
- HNL
纯化方法 Protein G purified UniProt编号 - P80188
产品使用声明 质量保证 Evaluated by Western Blotting in human lung tissue lysate.
Western Blotting Analysis: 1 µg/mL of this antibody detected Lipocalin-2 in 10 µg of human lung tissue lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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