merck millipore,默克密理愽
  • merck millipore,默克密理博,MABN448,Anti-ENC-1 Antibody, clone 1H8.1

  • merck millipore,默克密理博,MABN448,Anti-ENC-1 Antibody, clone 1H8.1

    产品名称：Anti-ENC-1 Antibody, clone 1H8.1
    产品型号：MABN448
    Anti-ENC-1 Antibody, clone 1H8.1 is a highly specific mouse monoclonal antibody, that targets Ectoderm-neural cortex-1 & has been tested in western blotting & IHC.

    merck millipore,默克密理博,MABN448,Anti-ENC-1 Antibody, clone 1H8.1

  • 产品介绍
  • merck millipore,默克密理博,MABN448,Anti-ENC-1 Antibody, clone 1H8.1

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    R, HIHC, WBMPurifiedMonoclonal Antibody
    描述
    产品目录编号 MABN448
    Replaces MABC685
    描述 Anti-ENC-1 Antibody, clone 1H8.1
    Alternate Names
    • p53-induced gene 10 protein
    • Ectoderm-neural cortex protein 1
    • ENC-1
    • Kelch-like protein 37
    • Nuclear matrix protein NRP/B
    背景信息 Ectoderm-neural cortex protein 1 (ENC1) as its name suggests is a protein involved in the regulation and differentiation of neural crest cells and neuronal development, as well as a protein involved in neuronal process formation later on. It is also known as nuclear matrix protein NRP/B. It is an actin binding protein that appears important in the organization of the actin cytoskeleton during neural fate specification and nervous system development. Its role in neuronal process formation is via its binding of RB1 (p110RB) when it is hypophosophorylated. ENC1 is widely expressed during development in the fetal heart, lung, and kidney. In the adult ENC1 is more restricted to nervous tissues primarily. It is abundant in adult brain, hippocampus, amygdale and spinal cord. There is also expression found in the adult pancreas. Numerous neuronal cancer cell lines and primary brain tumors also express ENC1. Localization is nuclear for the most part but in some cancer cells cytoplasmic staining is also observed. Its role in tumors is as an oncogene as studies suggest that both amplification and alteration of ENC1 may lead to tumor development and growth. Moreover ENC1 plays a role in the oxidative stress response as a regulator of the transcription factor Nrf2, and expression of this gene may play a role in malignant transformation as well.
    产品信息
    格式 Purified
    演示 Purified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
    应用
    应用 Anti-ENC-1 Antibody, clone 1H8.1 is a highly specific mouse monoclonal antibody, that targets Ectoderm-neural cortex-1 & has been tested in western blotting & IHC.
    主要应用
    • Immunohistochemistry
    • Western Blotting
    应用说明 Western Blotting Analysis: 1 µg/mL from a representative lot detected ENC-1 in 10 µg of rat hippocampus tissue.

    Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected ENC-1 in human cerebellum and cerebral cortex tissue.
    生物信息
    免疫原品种 GST-tagged recombinant protein corresponding to human ENC-1.
    克隆 1H8.1
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Mouse
    同种型 IgG2aκ
    品种反应性 RatHuman
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NP_001243503
    基因符号
    • PIG10
    • ENC1
    • NRPB
    纯化方法 Protein G purified
    UniProt编号
    • O14682
    产品使用声明
    质量保证 Evaluated by Western Blotting in human hippocampus tissue.

    Western Blotting Analysis: 1 µg/mL of this antibody detected ENC-1 in 10 µg of human hippocampus tissue.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 1 year at 2-8°C from date of receipt.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,MABN448,Anti-ENC-1 Antibody, clone 1H8.1

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下一件merck millipore产品：merck millipore,默克密理博,ABT28,Anti-Autotaxin Antibody


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