merck millipore,默克密理愽
  • merck millipore,默克密理博,MABN378,Anti-Potassium Channel Kv10.1 Antibody, clone 56

  • merck millipore,默克密理博,MABN378,Anti-Potassium Channel Kv10.1 Antibody, clone 56

    产品名称：Anti-Potassium Channel Kv10.1 Antibody, clone 56
    产品型号：MABN378
    Detect Kv10.1 using this mouse monoclonal antibody, Anti-Potassium Channel Kv10.1 Antibody, clone 56 validated for use in IHC, Activity Assay & Immunofluorescence.

    merck millipore,默克密理博,MABN378,Anti-Potassium Channel Kv10.1 Antibody, clone 56

  • 产品介绍
  • merck millipore,默克密理博,MABN378,Anti-Potassium Channel Kv10.1 Antibody, clone 56

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    R, HACT, IHCMPurifiedMonoclonal Antibody
    描述
    产品目录编号 MABN378
    描述 Anti-Potassium Channel Kv10.1 Antibody, clone 56
    Alternate Names
    • eag1
    • Potassium voltage-gated channel subfamily H member 1
    • Ether-a-go-go potassium channel 1
    • EAG channel 1
    • h-eag
    • hEAG1
    • Voltage-gated potassium channel subunit Kv10.1
    • hEag1 Potassium channel
    背景信息 Potassium Channel Kv10.1 is also known as Potassium voltage-gated channel subfamily H member 1, Ether-a-go-go potassium channel 1 (EAG channel 1, h-eag, or hEAG1) and Voltage-gated potassium channel subunit Kv10.1. Potassium Channel Kv10.1 is a pore-forming (alpha) subunit of voltage-gated, non-inactivating, delayed rectifier potassium channel. Potassium Channel Kv10.1 mediates IK(NI) current in myoblasts, and can be modulated by cAMP as well as subunit assembly. Potassium Channel Kv10.1 is highly expressed in myoblasts at the onset of fusion and brain tissue. It is not found in normal epithelial cells, but has been detected in HeLa (cervical carcinoma), SH-SY5Y (neuroblastoma) and MCF-7 (epithelial tumor) cells.
    产品信息
    格式 Purified
    控制
    • Rat brain tissue
    演示 Purified mouse monoclonal IgG2bκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
    应用
    应用 Detect Kv10.1 using this mouse monoclonal antibody, Anti-Potassium Channel Kv10.1 Antibody, clone 56 validated for use in IHC, Activity Assay & Immunofluorescence.
    主要应用
    • Activity Assay
    • Immunohistochemistry
    应用说明 Immunohistochemistry Analysis: A 1:250 dilution from a representative lot detected Potassium Channel Kv10.1 in human thalamus and cerebellum tissues.

    Immunocytochemistry Analysis: A representative lot detected Potassium Channel Kv10.1 in transfected CHO-K1 and HEK293 cells (Gomez-Varela, D., et al. (2007). Cancer Res. 67(15):7343-7349.).

    Activity Assay Analsyis: A representative lot from an independent laboratory inhibited anchorage-independent cancer cell growth in vitro (Gomez-Varela, D., et al. (2007). Cancer Res. 67(15):7343-7349.; Chen, Y., et al. (2011). PLoS One. 6(5):e19257.).

    Activity Assay Analysis: A representative lot from independent laboratories inhibited Potassium Channel Kv10.1 currents in transfected HEK293 cells (Gomez-Varela, D., et al. (2007). Cancer Res. 67(15):7343-7349.).

    Activity Assay Analysis: A representative lot from an independent laboratory inhibited cellular proliferation and
    migration of certain Acute myeloid leukemia cell lines and primary cultured AML cells in vitro (Agarwal, J. R., et al. (2010). Mol Cancer. 9:18.).
    生物信息
    免疫原品种 Recombinant protein corresponding to the extracellular domain of human Potassium Channel Kv10.1.
    表位 Extracellular domain
    克隆 56
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Mouse
    特异性 This antibody recognizes the extracellular, C-terminus domain of Potassium Channel Kv10.1. Additionally, this antibody does not cross react with hEag2 (Gomez-Varela, D., et al. (2007). Cancer Res. 67(15):7343-7349.).
    同种型 IgG2bκ
    品种反应性 RatHuman
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NP_002229
    基因符号
    • EAG1
    • KCNH1
    • EAG
    纯化方法 Protein G purified
    UniProt编号
    • O95259
    产品使用声明
    质量保证 Evaluated by Immunohistochemistry Analysis in rat frontal lobe tissue.

    Immunohistochemistry Analysis: A 1:50 dilution of this antibody detected Potassium Channel Kv10.1 in rat frontal lobe tissue.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 1 year at 2-8°C from date of receipt.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,MABN378,Anti-Potassium Channel Kv10.1 Antibody, clone 56

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