merck millipore,默克密理愽
  • merck millipore,默克密理博,23-029M,UbcH5a Protein, active, 250 µg

  • merck millipore,默克密理博,23-029M,UbcH5a Protein, active, 250 µg

    产品名称：UbcH5a Protein, active, 250 µg
    产品型号：23-029M
    Active, full length, recombinant human UbcH5a. N-terminal HA, 6His-tagged. For use in Enzyme Assays. Functions as an E2 enzyme in ubiquitination assays.

    merck millipore,默克密理博,23-029M,UbcH5a Protein, active, 250 µg

  • 产品介绍
  • merck millipore,默克密理博,23-029M,UbcH5a Protein, active, 250 µg

    重要规格表

    主要应用 品种 级联部件
    EAHumanE2
    描述
    产品目录编号 23-029M
    品牌系列 Upstate
    商名
    • Upstate
    描述 UbcH5a Protein, active, 250 µg
    长描述 N-terminal HA, 6His-tagged, recombinant human UbcH5a full length, expressed in E.coli. Purified using immobilized metal affinity chromatography.
    Alternate Names
    • UBE2D1
    • Ubiquitin-conjugating enzyme E2 D1
    • Ubiquitin-protein ligase D1
    • Ubiquitin-conjugating enzyme E2-17 kDa 1
    • UBC4/5 homolog
    • Stimulator of Fe transport (SFT)
    • UbcH5
    背景信息 Ubiquitin-conjugating (E2) enzymes are characterized by the presence of a highly conserved ubiquitin-conjugating domain which accommodates ATP-activated ubiquitin (Ub) via a covalently linked thioester onto its active-site residue. E2 enzymes act via selective protein-protein interactions with the ubiquitin-activating E1 enzyme and ubiquitin ligase E3 enzymes and are able to differentiate effects on downstream substrates, either with a single Ub molecule or an Ub chain. While E3s are involved in substrate selection, E2s are the main determinants for selection of the lysine to construct Ub chains, which thereby directly control the cellular fate of the substrate. The UbcH5 family (UbcH5a, UbcH5b and UbcH5c) have been shown to be the most active class of E2 enzymes in cell extracts and are associated with the regulation of a number of transcription factors, including p53 and c-Myc.
    应用
    应用 Active, full length, recombinant human UbcH5a. N-terminal HA, 6His-tagged. For use in Enzyme Assays. Functions as an E2 enzyme in ubiquitination assays.
    主要应用
    • Enzyme Assay
    生物信息
    品种 Human
    特异活性 For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
    级联部件 E2
    Entrez基因编号
    • NM_003338 (GenBank Number)
    纯化方法 Purified using immobilized metal affinity chromatography.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    包装信息
    数量 250 µg

    merck millipore,默克密理博,23-029M,UbcH5a Protein, active, 250 µg

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