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merck millipore,默克密理博,AB10537,Anti-Sox4 Antibody
产品名称：Anti-Sox4 Antibody
产品型号：AB10537
Use Anti-Sox4 Antibody (Rabbit Polyclonal Antibody) validated in IHC to detect Sox4 also known as SRY (sex determining region Y)-box 4, ecotropic viral integration site 16.
merck millipore,默克密理博,AB10537,Anti-Sox4 Antibody
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 M IHC Rb Serum Polyclonal Antibody 描述 产品目录编号 AB10537 描述 Anti-Sox4 Antibody Alternate Names - SRY-box containing gene 4
- SRY (sex determining region Y)-box 4
- ecotropic viral integration site 16
- SRY-related HMG-box gene 4
背景信息 Sox4 is a protein transcription factor belonging to a family of transcription factors consisting of well over 14 members and 7 different subgroups. Members of the Sox family are characterized by DNA binding domains showing strong similarity to HMG box domains.
Proteins belonging to the Sox family are involved in various phases of embryonic development including; neural development, hemopoiesis, lens development, chondrogenesis, and sex determination as well as cell fate. Sox4 is a part of the C subgroup of Sox proteins, and is involved in B cell and endocardial ridge development. During embryonic development, Sox4 expression has been observed in several tissues including; lung, gonads, embryonic heart, mesonephros, CNS, thymus, tooth buds, and T and pre-B cells. Sox4 has also been observed in mature tissue, especially in the pancreas, heart, lung, CHS, thymus, and gonads. Recent studies have linked overexpression of Sox4 to the development of various types of tumors and cancers, and indicating a potential for Sox4 as a therapeutic marker.产品信息 格式 Serum 控制 - Mouse embryo pancreas tissue
演示 Rabbit polyclonal serum containing 0.05% sodium azide. 应用 应用 Use Anti-Sox4 Antibody (Rabbit Polyclonal Antibody) validated in IHC to detect Sox4 also known as SRY (sex determining region Y)-box 4, ecotropic viral integration site 16. 主要应用 - Immunohistochemistry
应用说明 Western Blotting: Using 1:1000 dilution of a representative lot of this antibody and lysate of human pancreas, a faint band was observed at ~48 kDa with a stronger uncharacterized band observed at ~38 kDa.
生物信息 免疫原品种 GST-tagged recombinant protein corresponding to mouse Sox4. 宿主 Rabbit 特异性 This antibody recognizes Sox4. 品种反应性 Mouse Species Reactivity Note Demonstrated to react with mouse. 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_033264
基因符号 - EVI16
- SOX4
纯化方法 Unpurified UniProt编号 - Q5SW95
产品使用声明 质量保证 Evaluated by Immunohistochemistry in mouse embryo pancreas tissue.
Immunohistochemistry Analysis: 1:300 dilution of this antibody detected Sox4 in mouse embryo pancreas tissue.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.包装信息 数量 100 µL
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