merck millipore,默克密理愽
  • merck millipore,默克密理博,MABE866,Anti-Mad2 Antibody, clone AS55-A12

  • merck millipore,默克密理博,MABE866,Anti-Mad2 Antibody, clone AS55-A12

    产品名称：Anti-Mad2 Antibody, clone AS55-A12
    产品型号：MABE866
    Anti-Mad2 Antibody, clone AS55-A12 is a highly specific mouse monoclonal antibody, that targets MAD2 & has been tested in western blotting & Immunofluorescence.

    merck millipore,默克密理博,MABE866,Anti-Mad2 Antibody, clone AS55-A12

  • 产品介绍
  • merck millipore,默克密理博,MABE866,Anti-Mad2 Antibody, clone AS55-A12

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    HWBMPurifiedMonoclonal Antibody
    描述
    产品目录编号 MABE866
    描述 Anti-Mad2 Antibody, clone AS55-A12
    Alternate Names
    • MAD2-like protein 1
    • Mitotic spindle assembly checkpoint protein MAD2A
    • HsMAD2
    • Mitotic arrest deficient 2-like protein 1
    背景信息 Mad2, also known as MAD2, MAD2L1, or Mitotic spindle assembly checkpoint protein MAD2A, is a mitotic spindle assembly checkpoint protein. The spindle checkpoint makes sure that all the chromosomes are aligned at the metaphase plate before anaphase begins which means that all chromosomes are attached to the spindle before anaphase can start. The spindle checkpoint becomes triggered when the chromosome(s) are unaligned. Mad2 then binds to the anaphase promoting complex (APC) and CDC20. This complex prevents the cell from transitioning into anaphase and ultimately from cell death or disease.
    产品信息
    格式 Purified
    演示 Purified mouse monoclonal IgG2b in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
    应用
    应用 Anti-Mad2 Antibody, clone AS55-A12 is a highly specific mouse monoclonal antibody, that targets MAD2 & has been tested in western blotting & Immunofluorescence.
    主要应用
    • Western Blotting
    应用说明 Western Blotting Analysis: A representative lot from an independent laboratory detected Mad2 in HeLa cell lysate (Santaguida, S., et al. (2011). EMBO J. 30(8):1508-1519.).

    Immunofluorescence Analysis: A representative lot from an independent laboratory detected Mad2 in PtK1 cells transfected with Alexa-Mad2 (De Antoni, A., et al. 2005. Curr Biol. 15(3):214-225.).

    Western Blotting Analysis: A representative lot from an independent laboratory detected Mad2 in HeLa cells transfected with pCMV expressing wild-type myc-tagged Mad2, and certain mutations of myc-tagged Mad2 (This mutant does not bind to the core of Mad1/Mad2) (De Antoni, A., et al. 2005. Curr Biol. 15(3):214-225.).
    生物信息
    免疫原品种 His-tagged recombinant protein corresponding to human Mad2.
    克隆 AS55-A12
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Mouse
    同种型 IgG2b
    品种反应性 Human
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NP_002349
    基因符号
    • MAD2
    • MAD2L1
    纯化方法 Protein G purified
    UniProt编号
    • Q13257
    产品使用声明
    质量保证 Evaluated by Western Blotting in HEK293 cell lysate.

    Western Blotting Analysis: 1 µg/mL of this antibody detected Mad2 in 10 µg of HEK293 cell lyate.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 1 year at 2-8°C from date of receipt.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,MABE866,Anti-Mad2 Antibody, clone AS55-A12

上一件merck millipore产品：merck millipore,默克密理博,14-484,PKCα Protein, active, 10 µg
下一件merck millipore产品：merck millipore,默克密理博,AB9402,Anti-Serotonin Receptor 1F Antibody


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