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品种反应性 主要应用 宿主 格式 抗体类型 H WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABT290 Replaces MABT467 描述 Anti-DSG2 Antibody Alternate Names - HDGC
- Desmoglein-2
- Cadherin family member 5
背景信息 Desmoglein-2 (DSG2) is a single-pass type I membrane protein. Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Desmosomal cadherins, consisting of four desmogleins (DSG1-4) and three desmocollins (DSC1-3) in humans, mediate adhesion through calcium-dependent homophilic/heterophilic interactions. DSG2 is widely expressed in epithelial and non-epithelial tissues such as the intestine, epidermis, testis, and heart. Mutations in DSG2 have been assoicated with familial arrhythmogenic right ventricular dysplasia type 10 (ARVD10) and cardiomyopathy dilated type 1BB (CMD1BB). 产品信息 格式 Affinity Purified 控制 - HepG2 cell lysate
演示 Purified rabbit polyclonal in buffer containing PBS with 0.02% sodium azide and 50% glycerol. 应用 应用 Detect the DSG2 protein using this Anti-DSG2 validated for use in WB. 主要应用 - Western Blotting
生物信息 免疫原品种 GST-tagged recombinant protein corresponding to human DSG2. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 品种反应性 Human 抗体类型 Polyclonal Antibody 基因符号 - CDHF5
- DSG2
纯化方法 Antigen Affinity purified UniProt编号 - Q14126
产品使用声明 质量保证 Evaluated by Western Blotting in HepG2 cell lysate.
Western Blotting Analysis: A 1:2,000 dilution of this antibody detected DSG2 in 30 µg of HepG2 cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.包装信息 数量 150 µL
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