merck millipore,默克密理博,MABD170,Anti-AFP Antibody, clone 6E6

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merck millipore,默克密理博,MABD170,Anti-AFP Antibody, clone 6E6
产品名称：Anti-AFP Antibody, clone 6E6
产品型号：MABD170
Anti-AFP Antibody, clone 6E6 is a highly specific mouse monoclonal antibody & that targets α-Fetoprotein & has been tested in western blotting.

merck millipore,默克密理博,MABD170,Anti-AFP Antibody, clone 6E6

产品介绍

merck millipore,默克密理博,MABD170,Anti-AFP Antibody, clone 6E6

重要规格表

品种反应性	主要应用	宿主	格式	抗体类型
H	WB	M	Purified	Monoclonal Antibody

描述
产品目录编号	MABD170
描述	Anti-AFP Antibody, clone 6E6
Alternate Names	Alpha-fetoglobulin Alpha-fetoprotein FETA Alpha-1-fetoprotein
背景信息	Alpha fetoprotein (AFP) or alternatively known as Alpha-1-fetoprotein or Alpha-fetoglobulin is encoded by the human gene named AFP/HPAFP is an important early fetal blood protein. It is a secreted protein found in the plasma of fetuses older than 4 weeks of age and reaches the highest levels at 12th-16th week of gestation and then drops to trace amounts after birth. It is produced by the fetal liver and yolk sac normally. In normal adults the level is very low, but AFP can be a marker associated with various cancers and in particular with liver cancer and hepatomas. Its function during development is thought to be similar to that of serum albumin binding various ions and fatty acids as well as bilirubin, but while AFP is the most abundant protein found in the human fetus its complete function is still largely unknown. AFP as a biomarker in infants is associated with various diseases, however, because AFP levels change normally over a wide range in the developing fetus accurate aging is essential. High levels of AFP may suggest that the developing baby has a neural tube defect such as spina bifida or anencephaly. High levels of AFP may also suggest defects with the esophagus or a failure of baby’s abdomen to close. Low levels of AFP and abnormal levels of hCG and estriol may indicate that the developing baby has Trisomy 21 (Down syndrome), Trisomy 18 (Edwards Syndrome) or another type of chromosome abnormality. EMD-Millipore’s Anti-AFP mouse monoclonal antibody has been tested in western blot on HepG2 and SMMC-7721 cell lysates.

产品信息
格式	Purified
控制	HepG2 and SMMC-7721 cell lysates
演示	Purified mouse monoclonal in PBS containing up to 0.1% sodium azide and 50% glycerol.

应用
应用	Anti-AFP Antibody, clone 6E6 is a highly specific mouse monoclonal antibody & that targets α-Fetoprotein & has been tested in western blotting.
主要应用	Western Blotting

生物信息
免疫原品种	Purified recombinant fragment of human AFP expressed in E. Coli.
克隆	6E6
宿主	Mouse
同种型	IgG2b
品种反应性	Human
抗体类型	Monoclonal Antibody
基因符号	HPAFP AFP
纯化方法	Protein G purified

产品使用声明
质量保证	Evaluated by Western Blotting in HepG2 and SMMC-7721 cell lysates. Western Blotting Analysis: A 1:500-2,000 dilution of this antibody detected AFP in HepG2 and SMMC-7721 cell lysates. Optimal working dilutions must be determined by end user.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.

储存和货运信息

存储条件

Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.