merck millipore,默克密理愽
  • merck millipore,默克密理博,573097,STAT3 Inhibitor III, WP1066

  • merck millipore,默克密理博,573097,STAT3 Inhibitor III, WP1066

    产品名称：STAT3 Inhibitor III, WP1066
    产品型号：573097
    The STAT3 Inhibitor III, WP1066, also referenced under CAS 857064-38-1, controls the biological activity of STAT3.

    merck millipore,默克密理博,573097,STAT3 Inhibitor III, WP1066

  • 产品介绍
  • merck millipore,默克密理博,573097,STAT3 Inhibitor III, WP1066

    重要规格表

    经验配方 CAS号
    C₁₇H₁₄BrN₃O857064-38-1
    描述
    概述 A cell-permeable AG 490 (Cat. No. 658401) tyrphostin analog that acts as an effective STAT3 pathway inhibitor and a much more potent antitumor agent than AG 490 in inhibiting malignant glioma growth both in cultures in vitro (IC50 = 5.6 and 3.7 µM in a viability assay using U87-MG and U373-MG, respectively; no inhibition against nontumor NHA at 10 µM) and in mice in vivo. Shown to cross blood-brain barrier in mice in vivo. Also available in InSolution™ format (Cat. No. 573129.
    产品目录编号 573097
    品牌系列 Calbiochem®
    参考
    参考 Iwamaru, A., et al. 2007. Oncogene, 26, 2435.
    产品信息
    CAS号 857064-38-1
    具有ATP竞争性 N
    形式 Off-white solid
    Hill配方 C₁₇H₁₄BrN₃O
    化学配方 C₁₇H₁₄BrN₃O
    Molar Mass 356.2
    可逆 N
    结构配方图像
    生物信息
    主靶 STAT3 pathway
    主靶IC50 5.6 and 3.7 µM in inhibiting malignant glioma growth in a viability assay using U87-MG and U373-MG, respectively
    纯度 ≥97% by HPLC
    理化信息
    细胞可渗透 Y
    溶解度 DMSO or EtOH
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Irritant
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,573097,STAT3 Inhibitor III, WP1066

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