merck millipore,默克密理愽
  • merck millipore,默克密理博,MAB1698,Anti-Desmin Antibody, clone 131-15014 (KN50-1-4)

  • merck millipore,默克密理博,MAB1698,Anti-Desmin Antibody, clone 131-15014 (KN50-1-4)

    产品名称：Anti-Desmin Antibody, clone 131-15014 (KN50-1-4)
    产品型号：MAB1698
    This Anti-Desmin Antibody, clone 131-15014 (KN50-1-4) is validated for use in IC, IH(P) for the detection of Desmin.

    merck millipore,默克密理博,MAB1698,Anti-Desmin Antibody, clone 131-15014 (KN50-1-4)

  • 产品介绍
  • merck millipore,默克密理博,MAB1698,Anti-Desmin Antibody, clone 131-15014 (KN50-1-4)

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    H, BICCMPurifiedMonoclonal Antibody
    描述
    产品目录编号 MAB1698
    Replaces 04-585
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-Desmin Antibody, clone 131-15014 (KN50-1-4)
    产品信息
    格式 Purified
    演示 Purified immunoglobulin. Liquid in 10 mM Phosphate buffer, 150 mM NaCl, pH 7.4, containing 0.1% sodium azide.
    应用
    应用 This Anti-Desmin Antibody, clone 131-15014 (KN50-1-4) is validated for use in IC, IH(P) for the detection of Desmin.
    主要应用
    • Immunocytochemistry
    应用说明 Immunocytochemistry: approximate concentration 40 μg/mL

    Immunohistochemistry (frozen or de-paraffinized tissue): approximate concentration 40 μg/mL

    Optimal dilutions must be determined by end user.
    生物信息
    克隆 131-15014 (KN50-1-4)
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Mouse
    特异性 Desmin
    同种型 IgG1
    品种反应性 HumanBovine
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NM_001927.3
    Entrez基因汇总 This gene encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.
    基因符号
    • desmin
    • DES
    • CSM2
    • FLJ41793
    • FLJ41013
    • FLJ39719
    • CSM1
    • FLJ12025
    • Desmin.
    • CMD1I
    非反应性品种
    • Rabbit
    UniProt编号
    • P17661
    UniProt汇总 FUNCTION: SwissProt: P17661 # Desmin are class-III intermediate filaments found in muscle cells. In adult striated muscle they form a fibrous network connecting myofibrils to each other and to the plasma membrane from the periphery of the Z-line structures.
    SIZE: 470 amino acids; 53536 Da
    SUBUNIT: Homopolymer.
    SUBCELLULAR LOCATION: Cytoplasm.
    DISEASE: SwissProt: P17661 # Defects in DES are the cause of desmin-related cardio- skeletal myopathy (CSM) [MIM:601419]; also known as desmin-related myopathy (DRM). CSM is characterized by skeletal muscle weakness associated with cardiac conduction blocks, arrhythmias, restrictive heart failure, and by intracytoplasmic accumulation of desmin-reactive deposits in cardiac and skeletal muscle cells. A desmin-related myopathy can have a distal onset, it is then known as hereditary distal myopathy (HDM). & Defects in DES are the cause of dilated cardiomyopathy 1I (CMD1I) [MIM:604765]. CMD1I is an autosomal form of dilated cardiomyopathy characterized by ventricular dilatation and impaired systolic function.
    SIMILARITY: SwissProt: P17661 ## Belongs to the intermediate filament family.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,MAB1698,Anti-Desmin Antibody, clone 131-15014 (KN50-1-4)

上一件merck millipore产品：merck millipore,默克密理博,MABN491,Anti-Brevican Antibody, clone N294A/6
下一件merck millipore产品：merck millipore,默克密理博,MAB1951F,Anti-Integrin β1 Antibody, clone P4G11, FITC conjugated


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