• merck millipore,默克密理博,412400,IQ-1 - CAS 331001-62-8 - Calbiochem
  • merck millipore,默克密理博,412400,IQ-1 - CAS 331001-62-8 - Calbiochem

    产品名称:IQ-1 - CAS 331001-62-8 - Calbiochem
    产品型号:412400
    A cell-permeable tetrahydroisoquinolinylidene compound that modulates Wnt/β-catenin signaling by targeting the PR72/130 subunit of PP2A and thereby blocking PP2A/Nkd complex formation.

    merck millipore,默克密理博,412400,IQ-1 - CAS 331001-62-8 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,412400,IQ-1 - CAS 331001-62-8 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₂₁H₂₂N₄O₂331001-62-8
    描述
    概述 A cell-permeable tetrahydroisoquinolinylidene compound that modulates Wnt/β-catenin signaling by targeting the PR72/130 subunit of PP2A and thereby blocking PP2A/Nkd complex formation, resulting in diminished β-catenin/p300 interaction and a concomitant increase in β-catenin/CBP usage. Co-adminitration of IQ-1 (4 µg/ml) and Wnt3a (100 ng/ml), but neither reagent alone, has been shown to be sufficient in maintaining long-term (>48 days) murine ESCs (Embryonic Stem Cells) pluripotency in the absence of serum.
    产品目录编号 412400
    品牌系列 Calbiochem®
    同义词 2-(4-Acetylphenylazo)-2-(3,3-dimethyl-3,4-dihydro-2H-isoquinolin-1-ylidene)-acetamide, Wnt Pathway Activator III
    参考
    参考 Miyabayashi, T., et al. 2007. Proc. Natl. Acad. Sci. USA 104, 5668.
    产品信息
    CAS号 331001-62-8
    形式 Orange solid
    Hill配方 C₂₁H₂₂N₄O₂
    化学配方 C₂₁H₂₂N₄O₂
    Molar Mass 362.4
    结构配方图像
    生物信息
    纯度 ≥95% by HPLC
    理化信息
    溶解度 DMSO
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,412400,IQ-1 - CAS 331001-62-8 - Calbiochem

上一件merck millipore产品:merck millipore,默克密理博,218759,Caspase-8 Inhibitor II - Calbiochem
下一件merck millipore产品:merck millipore,默克密理博,616395,Transferrin, Apo-, Human Plasma



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