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merck millipore,默克密理博,218759,Caspase-8 Inhibitor II - Calbiochem
产品名称:Caspase-8 Inhibitor II - Calbiochem
产品型号:218759
The Caspase-8 Inhibitor II controls the biological activity of Caspase-8. This small molecule/inhibitor is primarily used for Cancer applications.
merck millipore,默克密理博,218759,Caspase-8 Inhibitor II - Calbiochem
- 产品介绍
重要规格表
经验配方 C₃₀H₄₃FN₄O₁₁ 描述 概述 A potent, cell-permeable, and irreversible inhibitor of caspase-8 and granzyme B. Effectively inhibits influenza virus-induced apoptosis in HeLa cells. Also inhibits granzyme B. When using with purified native or recombinant enzyme, pretreatment with an esterase is required. A 5 mM (250 µg/76 µl) solution of Z-IETD-FMK (Cat. No. 218840) in DMSO is also available. 产品目录编号 218759 品牌系列 Calbiochem®
同义词 Z-IE(OMe)TD(OMe)-FMK, Granzyme B Inhibitor III 参考 参考 Takizawa, T., et al. 1999. Microbiol. Immunol. 43, 245.
Martin, D.A., et al. 1998. J. Biol. Chem. 273, 4345.
Sweeney, E.A., et al. 1998. FEBS Lett. 425, 61.
Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.产品信息 具有ATP竞争性 N 形式 White to yellow powder Hill配方 C₃₀H₄₃FN₄O₁₁ 化学配方 C₃₀H₄₃FN₄O₁₁ Molar Mass 654.7 肽序列 Z-Ile-Glu(OMe)-Thr-Asp(OMe)-CH₂F* 可逆 N 生物信息 主靶 caspase-8 纯度 single spot by TLC 理化信息 细胞可渗透 Y 溶解度 DMSO 肽序列 Z-Ile-Glu(OMe)-Thr-Asp(OMe)-CH₂F* 储存和货运信息 货运代码 Ambient Temperature Only
毒性 Standard Handling
储存 -20°C
防潮 Protect from moisture
无需冷冻 No
特殊指南 Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 8 months at -20°C.
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