merck millipore,默克密理博,MABC689,Anti-NUP96 Antibody, clone EPR6678, rabbit monoclonal

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merck millipore,默克密理博,MABC689,Anti-NUP96 Antibody, clone EPR6678, rabbit monoclonal
产品名称：Anti-NUP96 Antibody, clone EPR6678, rabbit monoclonal
产品型号：MABC689
Anti-NUP96 Antibody, clone EPR6678 is a highly specific rabbit monoclonal antibody, that targets Nuclear pore protein 96 & has been tested in western blotting & IHC.

merck millipore,默克密理博,MABC689,Anti-NUP96 Antibody, clone EPR6678, rabbit monoclonal

产品介绍

merck millipore,默克密理博,MABC689,Anti-NUP96 Antibody, clone EPR6678, rabbit monoclonal

重要规格表

品种反应性	主要应用	宿主	格式	抗体类型
H	IHC, WB	Rb	Unpurified	Monoclonal Antibody

描述
产品目录编号	MABC689
描述	Anti-NUP96 Antibody, clone EPR6678, rabbit monoclonal
Alternate Names	Nucleoporin Nup96 Nuclear pore complex protein Nup98-Nup96 Nuclear pore complex protein Nup98 98 kDa nucleoporin Nucleoporin Nup98 Nuclear pore complex protein Nup96 96 kDa nucleoporin
背景信息	Nuclear pore protein 96 (NUP96) named after its molecular weight, or often in the literature as its yeast name, Nup145C, is one of them and NUP96 is made from the autocatalytic cleavage of a larger precursor protein named the Nuclear Pore Complex protein Nup98-Nup96, which also happens to be the source of NUP98 another important nuclear pore protein. NUC96 is found on both the nuclear and cytoplasmic sides of the NPC, whereas NUP98 apparently shuttles between the cytoplasmic side and the nucleoplasmic side of the NPC. Nup96 is part of a NP heptameric complex in the nuclear pore complex. Nup96 complexes with Sec13 in the middle of the heptamer complex. The function of the heptamer is to coat the curvature of the nuclear pore complex between the inner and outer nuclear membranes. Nup96 is predicted to be an alpha helical solenoid. The interaction between Nup96 and Sec13 is at the point of curvature in the heptameric complex. Interestingly, NUP96 and NUP98 also have a crucial role in the function of the immune system and are up regulated by interferons in response to viral infections. A heterozygous mutation in NUP96 has been shown to affect the expression of interferon-regulated genes and to disrupt the normal function of macrophages, and B and T lymphocytes, with no detectable gross pathological abnormalities in other organs. Moreover, the role of Nup96 in the immune response seems to be evolutionarily conserved, as NUP96 in Arabidopsis thaliana has also been shown to be required for the basal defense and resistance responses mediated by plant immune sensors. EMD-Millipore’s Anti-NUP96 rabbit monoclonal has been tested in western blot using multiple human cell lysates and in immunohistochemistry on paraffin embedded human colon tissue.

产品信息
格式	Unpurified
控制	HeLa, SHSY5Y, and Caco-2 cell lysates
演示	Rabbit monoclonal in buffer containing PBS with up to 0.1% sodium azide, 0.05% BSA, and 50% glycerol.

应用
应用	Anti-NUP96 Antibody, clone EPR6678 is a highly specific rabbit monoclonal antibody, that targets Nuclear pore protein 96 & has been tested in western blotting & IHC.
主要应用	Immunohistochemistry Western Blotting
应用说明	Immunohistochemistry Analysis: A 1:50-100 dilution from a representative lot detected NUP96 in human colon tissue. Optimal working dilutions must be determined by end user.

生物信息
免疫原品种	Synthetic peptide corresponding to human NUP96.
克隆	EPR6678
宿主	Rabbit
品种反应性	Human
抗体类型	Monoclonal Antibody
基因符号	ADAR2 NUP96 NUP98
纯化方法	Unpurified
UniProt编号	P52948

产品使用声明
质量保证	Evaluated by Western Blotting in HeLa, SHSY5Y, and Caco-2 cell lysates. Western Blotting Analysis: A 1:1,000-10,000 dilution of this antibody detected NUP96 in HeLa, SHSY5Y, and Caco-2 cell lysates.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.

储存和货运信息

存储条件

Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.