merck millipore,默克密理愽
  • merck millipore,默克密理博,MABC668,Anti-CD73, clone EPR6114, Rabbit Monoclonal Antibody

  • merck millipore,默克密理博,MABC668,Anti-CD73, clone EPR6114, Rabbit Monoclonal Antibody

    产品名称：Anti-CD73, clone EPR6114, Rabbit Monoclonal Antibody
    产品型号：MABC668
    Please note that this product will not be available for sale after March 15, 2015. Please select one of the other antibodies against this target.

    merck millipore,默克密理博,MABC668,Anti-CD73, clone EPR6114, Rabbit Monoclonal Antibody

  • 产品介绍
  • merck millipore,默克密理博,MABC668,Anti-CD73, clone EPR6114, Rabbit Monoclonal Antibody

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    HIHC, WBRbUnpurifiedMonoclonal Antibody
    描述
    产品目录编号 MABC668
    描述 Anti-CD73, clone EPR6114, Rabbit Monoclonal Antibody
    Alternate Names
    • CD antigen CD73
    • 5'-nucleotidase
    • 5'-NT
    • Ecto-5'-nucleotidase
    背景信息 CD73 is now known to be an enzyme called 5'-nucleotidase, or ecto-5-prime-nucleotidase with a gene name of NT5E, NT5, or NTE, and is the protein located on the plasma membrane. CD73 hydrolyzes extracellular nucleotides into membrane permeable nucleosides and free phosphate. Its preferred substrate is AMP, and CD73 is a key enzyme in the regulation of adenosinergic signaling. The enzyme consists of a dimer of 2 identical 70-kD subunits bound by a glycosyl phosphatidyl inositol linkage to the external face of the plasma membrane. In immunology, CD73 is a marker for mature lymphocytes. Consequently, a deficiency of CD73 occurs in a variety of immunodeficiency diseases. Interestingly, recent research indicates that inhibiting CD73 activity could help treat cancer and prevent metastasis, and that CD73 is necessary for effective T-lymphocyte invasion in the brain under various immunological disease states, so by inhibiting its activity neuroinflammation could be potentially be mediated.
    产品信息
    格式 Unpurified
    演示 Rabbit monoclonal in buffer containing PBS with up to 0.1% sodium azide, 0.05% BSA, and 50% glycerol.
    应用
    应用 Please note that this product will not be available for sale after March 15, 2015. Please select one of the other antibodies against this target.
    主要应用
    • Immunohistochemistry
    • Western Blotting
    应用说明 Immunohistochemistry Analysis: A 1:100-250 dilution from a representative lot detected CD73 in human tonsil tissue.

    Produced in collaboration with Epitomics™
    生物信息
    免疫原品种 Synthetic peptide corresponding to human CD73.
    克隆 EPR6114
    浓缩 Please refer to lot specific datasheet.
    宿主 Rabbit
    同种型 IgG
    品种反应性 Human
    Species Reactivity Note Human
    抗体类型 Monoclonal Antibody
    基因符号
    • NTE
    • NT5E
    • NT5
    纯化方法 Unpurified
    UniProt编号
    • P21589
    产品使用声明
    质量保证 Evaluated by Western Blotting in human fetal liver, A375, and HepG2 lysates.

    Western Blotting Analysis: A 1:1,000-10,000 dilution of this antibody detected CD73 in human fetal liver, A375, and HepG2 lysates.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 1 year at -20°C from date of receipt.
    Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
    Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.
    包装信息
    数量 100 µL

    merck millipore,默克密理博,MABC668,Anti-CD73, clone EPR6114, Rabbit Monoclonal Antibody

上一件merck millipore产品：merck millipore,默克密理博,14-749,TAO1 Protein, active, 10 µg
下一件merck millipore产品：merck millipore,默克密理博,612200,Tissue Plasminogen Activator, Human


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