merck millipore,默克密理愽
  • merck millipore,默克密理博,MABC196,Anti-Chitinase-3-like protein 1 (YKL-40) Antibody, clone mAY

  • merck millipore,默克密理博,MABC196,Anti-Chitinase-3-like protein 1 (YKL-40) Antibody, clone mAY

    产品名称：Anti-Chitinase-3-like protein 1 (YKL-40) Antibody, clone mAY
    产品型号：MABC196
    This Anti-Chitinase-3-like protein 1 (YKL-40) Antibody, clone mAY is validated for use in Western Blotting, IHC, Activity Assay for the detection of Chitinase-3-like protein 1 (YKL-40).

    merck millipore,默克密理博,MABC196,Anti-Chitinase-3-like protein 1 (YKL-40) Antibody, clone mAY

  • 产品介绍
  • merck millipore,默克密理博,MABC196,Anti-Chitinase-3-like protein 1 (YKL-40) Antibody, clone mAY

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    HACT, WB, IHCMPurifiedMonoclonal Antibody
    描述
    产品目录编号 MABC196
    描述 Anti-Chitinase-3-like protein 1 (YKL-40) Antibody, clone mAY
    Alternate Names
    • YKL-40
    • Chitinase-3-like protein 1
    • 39 kDa synovial protein
    • Cartilage glycoprotein 39
    • CGP-39
    • GP-39
    • hCGP-39
    背景信息 YKL-40 (Chitinase-3-like protein 1; human cartilage glycoprotein 39) is a secreted glycoprotein belonging to the glycosyl hydrolase 18 (GH18) family. It is found primarily in chondrocytes, activated macrophages, and hepatocytes. The precise biological function of YKL-40 is still unknown; however, recent studies suggest that YKL-40 may play a role in cell differentiation and inflammation. YKL-40 is elevated in the sera of patients with inflammatory diseases or cancer, and it is currently being investigated as a potential biomarker for these conditions.
    产品信息
    格式 Purified
    控制
    • MG-63 conditioned media
    演示 Purified mouse monoclonal IgG1κ in buffer containing PBS without preservatives.
    应用
    应用 This Anti-Chitinase-3-like protein 1 (YKL-40) Antibody, clone mAY is validated for use in Western Blotting, IHC, Activity Assay for the detection of Chitinase-3-like protein 1 (YKL-40).
    主要应用
    • Activity Assay
    • Western Blotting
    • Immunohistochemistry
    应用说明 Immunocytochemistry Analysis: A representative lot from an independent laboratory detected Chitinase-3-like protein 1 (YKL-40) in U87 cells (This protein blocks tumor angiogenesis tube formation and progression (Faibish, M., et al. (2011). Mol Cancer Ther. 10(5):742-751.)).

    Activity Assay Analysis: A representative lot from an independent laboratory neutralized Chitinase-3-like protein 1 in a neutralization assay (Faibish, M., et al. (2011). Mol Cancer Ther. 10(5):742-751.).
    生物信息
    免疫原品种 Recombinant protein corresponding to human Chitinase-3-like protein 1 (YKL-40).
    克隆 mAY
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Mouse
    同种型 IgG1κ
    品种反应性 Human
    Species Reactivity Note Demonstrated to react with Human.
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • ">NP_001267
    基因符号
    • CHI3L1
    纯化方法 Protein G purified
    UniProt编号
    • P36222
    产品使用声明
    质量保证 Evaluated by Western Blot in MG-63 conditioned media.

    Western Blot Analysis: 0.5 µg/mL of this antibody detected Chitinase-3-like protein 1 (YKL-40) in 10 µg of MG-63 conditioned media (This protein blocks tumor angiogenesis tube formation and progression (Faibish, M., et al. (2011). Mol Cancer Ther. 10(5):742-751.)).
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 1 year at -20°C from date of receipt.
    Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,MABC196,Anti-Chitinase-3-like protein 1 (YKL-40) Antibody, clone mAY

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