merck millipore,默克密理愽
  • merck millipore,默克密理博,579050,TAPI-0 - CAS 143457-40-3 - Calbiochem

  • merck millipore,默克密理博,579050,TAPI-0 - CAS 143457-40-3 - Calbiochem

    产品名称：TAPI-0 - CAS 143457-40-3 - Calbiochem
    产品型号：579050
    A hydroxamate-based inhibitor of collagenase, gelatinase, and TACE (TNF-α converting enzyme/ADAM17; IC₅₀ = 100 nM).

    merck millipore,默克密理博,579050,TAPI-0 - CAS 143457-40-3 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,579050,TAPI-0 - CAS 143457-40-3 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₂₄H₃₂N₄O₅143457-40-3
    描述
    概述 A hydroxamate-based inhibitor of collagenase, gelatinase, and TACE (TNF-α converting enzyme/ADAM17; IC50 = 100 nM). Blocks spontaneous and PMA-induced release of TNF-α in transfected COS 7 cells.
    产品目录编号 579050
    品牌系列 Calbiochem®
    同义词 N-(R)-[2-(Hydroxyaminocarbonyl)methyl]-4-methylpentanoyl-L-naphthylalanyl-L-alanine Amide, TNF-α Protease Inhibitor-0
    参考
    参考 Hooper, N.M., et al. 1997. Biochem. J. 321, 265.
    Mullberg, J., et al. 1995. J. Immunol. 155, 5198.
    Mohler, K.M., et al. 1994. Nature 370, 218.
    产品信息
    CAS号 143457-40-3
    具有ATP竞争性 N
    声明 Manufactured exclusively by Peptides International, Louisville, Kentucky, USA.
    形式 White solid
    Hill配方 C₂₄H₃₂N₄O₅
    化学配方 C₂₄H₃₂N₄O₅
    Molar Mass 456.5
    吸湿 Hygroscopic
    可逆 N
    结构配方图像
    生物信息
    主靶 TNF-α converting enzyme/ADAM17
    主靶IC50 100 nM against TACE (TNF-α converting enzyme/ADAM17)
    纯度 ≥96% by HPLC
    理化信息
    细胞可渗透 N
    溶解度 50% acetic acid or DMSO
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 -20°C
    避光 Protect from light
    吸湿 Hygroscopic
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,579050,TAPI-0 - CAS 143457-40-3 - Calbiochem

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