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描述 产品目录编号 14-560M 品牌系列 Upstate
商名 - Upstate
描述 EphA2 Protein, active, 250 µg 概述 N-terminal His6-tagged, recombinant human EphA2 residues 596-900 应用 应用 Active, N-terminal His6-tagged, recombinant human EphA2 residues 596-900, for use in Kinase Assays. 主要应用 - Kinase Assay
生物信息 来源 Expressed by baculovirus in Sf21 insect cells 品种 Human 特异活性 For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme. Entrez基因编号 - NM_004431.2
Entrez基因汇总 This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. 基因符号 - ECK
- EPHA2
- EphA2
蛋白靶 EphA2 纯化方法 Ni2+/NTA-agarose 靶子系列 TK UniProt编号 - P29317
UniProt汇总 FUNCTION: SwissProt: P29317 # Receptor for members of the ephrin-A family. Binds to ephrin-A1, -A3, -A4 and -A5.
SIZE: 976 amino acids; 108254 Da
SUBUNIT: Interacts with SLA (By similarity). Interacts with INPPL1/SHIP2.
SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
TISSUE SPECIFICITY: Expressed most highly in tissues that contain a high proportion of epithelial cells, e.g., skin, intestine, lung, and ovary.
SIMILARITY: SwissProt: P29317 ## Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily. & Contains 2 fibronectin type-III domains. & Contains 1 protein kinase domain. & Contains 1 SAM (sterile alpha motif) domain.产品使用声明 质量保证 Routinely evaluated by phosphorylation of Poly (Glu4-Tyr) (4:1) 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 6 months at -70°C 包装信息 数量 250 µg 包装 Also available in 10 μg size (cat#14-560) and in bulk (cat# 14-560-K).
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