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merck millipore,默克密理博,MABC164,Anti-Arl1 Antibody, clone 11A12.1
产品名称:Anti-Arl1 Antibody, clone 11A12.1
产品型号:MABC164
Detect ADP-ribosylation factor-like 1 protein using this mouse monoclonal antibody, Anti-Arl1 Antibody, clone 11A12.1 validated for use in western blotting & ICC.
merck millipore,默克密理博,MABC164,Anti-Arl1 Antibody, clone 11A12.1
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H ICC, WB M Purified Monoclonal Antibody 描述 产品目录编号 MABC164 描述 Anti-Arl1 Antibody, clone 11A12.1 Alternate Names - ADP-ribosylation factor-like protein 1
背景信息 The protein named Arl1 or ADP-ribosylation factor-like 1 protein and encoded by the gene ARL1, is a member ADP-ribosylation factor like family that plays an important role in Golgi function and maintenance. The small G protein Arf1 regulates Golgi traffic and is activated by two related types of guanine nucleotide exchange factors (GEFs). GBF1 acts at the cis-Golgi, whereas BIG1 and its close paralog BIG2 act at the trans-Golgi membranes, both work to activate Arl1. Arl1’s GTP-bound form interacts with GOLGA1. The GTP-bound form also interacts with GOLGA4 and RGPD8 and directly interacts with ARFIP2; this interaction leads to a > 4-fold increase in the amount of bound GTP at steady state level, and ARL1 binds to SCOC, preferentially in its GTP-bound form. Arl1 is localized to the Golgi apparatus membrane, the cytoplasmic side. Arl1 is expressed in heart, liver, lung, kidney, placenta, pancreas and skeletal muscle tissues. 产品信息 格式 Purified 演示 Purified mouse monoclonal IgG2bκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Detect ADP-ribosylation factor-like 1 protein using this mouse monoclonal antibody, Anti-Arl1 Antibody, clone 11A12.1 validated for use in western blotting & ICC. 主要应用 - Immunocytochemistry
- Western Blotting
应用说明 Immunocytochemistry Analysis: A 1:50-250 dilution from a representative lot detected Arl1 in HeLa and MCF-7 cells. 生物信息 免疫原品种 GST-tagged recombinant protein corresponding to human Arl1. 克隆 11A12.1 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Mouse 同种型 IgG2bκ 品种反应性 Human 抗体类型 Monoclonal Antibody Entrez基因编号 - NP_001168
基因符号 - ARL1
纯化方法 Protein G purified UniProt编号 - P40616
产品使用声明 质量保证 Evaluated by Western Blotting in HEp-2 cell lysate.
Western Blotting Analysis: 0.2 µg/mL of this antibody detected Arl1 in 10 µg of HEp-2 cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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