merck millipore,默克密理愽
  • merck millipore,默克密理博,MAB5350,Anti-Choline Acetyltransferase Antibody, clone 28C4

  • merck millipore,默克密理博,MAB5350,Anti-Choline Acetyltransferase Antibody, clone 28C4

    产品名称：Anti-Choline Acetyltransferase Antibody, clone 28C4
    产品型号：MAB5350
    Anti-Choline Acetyltransferase Antibody, clone 28C4 detects level of Choline Acetyltransferase & has been published & validated for use in ELISA, IH & WB.

    merck millipore,默克密理博,MAB5350,Anti-Choline Acetyltransferase Antibody, clone 28C4

  • 产品介绍
  • merck millipore,默克密理博,MAB5350,Anti-Choline Acetyltransferase Antibody, clone 28C4

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    R, Gp, H, MkWB, ELISA, IHCMPurifiedMonoclonal Antibody
    描述
    产品目录编号 MAB5350
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-Choline Acetyltransferase Antibody, clone 28C4
    Alternate Names
    • ChAT
    产品信息
    格式 Purified
    演示 Purified immunoglobulin. Liquid.
    应用
    应用 Anti-Choline Acetyltransferase Antibody, clone 28C4 detects level of Choline Acetyltransferase & has been published & validated for use in ELISA, IH & WB.
    主要应用
    • Western Blotting
    • ELISA
    • Immunohistochemistry
    应用说明 Western blotting: 1:1,000-1:10,000 using a high sensitivity ECL kit. Recognizes a protein of ~67 kDa. May also recognize a protein of 35 kDa which is thought to be a degradation product. Suggested dilution buffer is TBS containing 5% skim milk powder and 0.05% Tween 20.

    Immunohistochemistry on free-floating frozen sections of Rhesus monkey brain fixed with 4% paraformaldehyde and coronal vibratome sections of rat brain fixed with 4% paraformaldehyde and 0.2% glutaraldehyde.

    ELISA (two side)

    Optimal working dilutions must be determined by end user.
    生物信息
    免疫原品种 Purified human placenta ChAT.
    克隆 28C4
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Mouse
    特异性 Reacts with Choline Acetyltransferase (ChAT).
    同种型 IgG
    品种反应性 RatGuinea PigHumanMonkey
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NM_020986.2
    • NM_020549.3
    • NM_020984.2
    • NM_020985.2
    Entrez基因汇总 Cholinergic systems are implicated in numerous neurologic functions. Alteration in some cholinergic neurons may account for the disturbances of Alzheimer disease. The protein encoded by this gene synthesizes the neurotransmitter acetylcholine. Alternative splice variants have been found that contain alternative 5' untranslated exons. Three of the four described splice variants encode identical 69 kDa proteins while one variant encodes both the 69 kDa and a larger 82 kDa protein.
    基因符号
    • EC 2.3.1.6
    • CHAT
    • ChAT
    • CMS1A2
    • CHOACTase
    • CMS1A
    UniProt编号
    • P28329
    UniProt汇总 FUNCTION: SwissProt: P28329 # Catalyzes the reversible synthesis of acetylcholine (ACh) from acetyl CoA and choline at cholinergic synapses.
    SIZE: 748 amino acids; 82568 Da
    DISEASE: SwissProt: P28329 # Defects in CHAT are the cause of familial infantile myasthenia gravis 2 (FIMG2) [MIM:254210, 254200]; also known as CMS-EA. FIMG2 patients have myasthenic symptoms since birth or early infancy, negative tests for anti-AChR antibodies, and abrupt episodic crises with increased weakness, bulbar paralysis, and apnea precipitated by undue exertion, fever, or excitement. Inheritance is autosomal recessive.
    SIMILARITY: SwissProt: P28329 ## Belongs to the carnitine/choline acetyltransferase family.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain at 2-8°C in undiluted aliquots for up to 6 months after date of receipt.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,MAB5350,Anti-Choline Acetyltransferase Antibody, clone 28C4

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