merck millipore,默克密理愽
  • merck millipore,默克密理博,AB152,Anti-Tyrosine Hydroxylase Antibody

  • merck millipore,默克密理博,AB152,Anti-Tyrosine Hydroxylase Antibody

    产品名称：Anti-Tyrosine Hydroxylase Antibody
    产品型号：AB152
    Anti-Tyrosine Hydroxylase Antibody detects level of TH and has been published and validated for use in ELISA, IF, IH, IH(P), IP and WB.

    merck millipore,默克密理博,AB152,Anti-Tyrosine Hydroxylase Antibody

  • 产品介绍
  • merck millipore,默克密理博,AB152,Anti-Tyrosine Hydroxylase Antibody

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    Ml, H, R, M, Fe, Ft, Sqd, DrWB, ELISA, IHCRbAffinity PurifiedPolyclonal Antibody
    描述
    产品目录编号 AB152
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-Tyrosine Hydroxylase Antibody
    Alternate Names
    • TH
    • Tyrosine 3-hydroxylase
    • Tyrosine 3-monooxygenase
    • tyrosine hydroxylase
    背景信息 Tyrosine hydroxylase (also know as Tyrosine 3-hydroxylase and Tyrosine 3-monooxygenase) plays an important role in the physiology of adrenergic neurons. It is the first and rate-limiting enzyme involved in the biosynthesis of the catecholamines Dopamine and Norepinephrine from tyrosine. TH is, therefore, a useful marker for dopaminergic and noradrenergic neurons. The enzymatic activity of TH requires ferrous ions as cofactors and is believed to be regulated by phosphorylation. At least four isoforms of human TH have been identified which result from alternative splicing.
    产品信息
    格式 Affinity Purified
    控制
    • POSITIVE CONTROL: Brain (corpus striatum, sympathetic nerve terminals) and adrenal glands.
      NEGATATIVE CONTROL: Liver.
    演示 Purified rabbit polyclonal in buffer containing liquid in 10 mM HEPES (pH 7.5), 150 mM NaCl (pH 7.5), 100 ug/mL BSA and 50% glycerol.
    应用
    应用 Anti-Tyrosine Hydroxylase Antibody detects level of TH and has been published and validated for use in ELISA, IF, IH, IH(P), IP and WB.
    主要应用
    • Western Blotting
    • ELISA
    • Immunohistochemistry
    应用说明 Immunohistochemistry:
    A previous lot of this antibody was uesd at 1:100-1:1,000 dilution, 4°C, for 1-3 days. Stains both fresh frozen and paraffin embedded tissue samples by indirect immunofluorescence and immunoperoxidase.

    Immunofluorescence:
    A previous lot of this antibody was used at 1:100-1:1,000 dilution.

    Immunoprecipitation:
    A previous lot of this antibody was used on Immunoprecipitation.

    ELISA:
    A previous lot of this antibody was used in ELISA.

    Optimal dilutions must be determined by the end user.
    生物信息
    免疫原品种 Denatured tyrosine hydroxylase from rat pheochromocytoma (denatured by sodium dodecyl sulfate).
    宿主 Rabbit
    特异性 Tyrosine hydroxylase. By western blot, AB152 selective labels a single band at approximately 62kDa (reduced) corresponding to Tyrosine Hydroxylase. It is expected that the antibody will react with most mammalian and many non-mammalian species. It has been reported that this antibody does not work on paraffin embedded human tissue.
    品种反应性 MolluskHumanRatMouseFelineFerretSquidDrosophila
    Species Reactivity Note Rat, mouse, ferret, feline, Aplysia (marine mollusc). It is expected that the antibody will react with most mammalian and many non-mammalian species. It has been reported that this antibody does not work on paraffin embedded human tissue.
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NM_012740.3
    Entrez基因汇总 Tyrosine hydroxylase is involved in the conversion of tyrosine to dopamine. As the rate-limiting enzyme in the synthesis of catecholamines, tyrosine hydroxylase has a key role in the physiology of adrenergic neurons.
    基因符号
    • EC 1.14.16.2
    • TH
    • TYH
    纯化方法 Affinity Purfied
    UniProt编号
    • P04177
    UniProt汇总 FUNCTION: SwissProt: P07101 # Plays an important role in the physiology of adrenergic neurons.
    COFACTOR: Fe(2+) ion.
    SIZE: 528 amino acids; 58524 Da
    TISSUE SPECIFICITY: Mainly expressed in the brain and adrenal glands.
    DISEASE: SwissProt: P07101 # Defects in TH are the cause of autosomal recessive Segawa syndrome [MIM:605407]; also known as DOPA-responsive dystonia. Typically, it begins in childhood or adolescence with progressive difficulty in walking and, in some cases, spasticity. Some cases present with parkinsonian symptoms in infancy and are referred to as autosomal recessive infantile parkinsonism.
    SIMILARITY: SwissProt: P07101 ## Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.
    产品使用声明
    质量保证 Routinely evaluated by Western Blot on PC12 lysates.

    Western Blot Analysis:
    1:1000 dilution of this lot detected tyrosine hydroxylase on 10 μg of PC12 lysates.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain frozen at -20ºC to -70ºC in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles. Do not store in a self defrosting freezer.
    包装信息
    数量 100 µL

    merck millipore,默克密理博,AB152,Anti-Tyrosine Hydroxylase Antibody

上一件merck millipore产品：merck millipore,默克密理博,14-751,Abl (Q252H) Protein, active, 10 µg
下一件merck millipore产品：merck millipore,默克密理博,573112,SPDP


相关产品

merck millipore,默克密理博,MAB5350,Anti-Choline Acetyltransferase Antibody, clone 28C4 merck millipore,默克密理博,MAB5350,Anti-Choline Acetyltransferase Antibody, clone 28C4

merck millipore,默克密理博,16-187,Anti-dimethyl-Histone H3 (Lys9) Antibody, biotin conjugate merck millipore,默克密理博,16-187,Anti-dimethyl-Histone H3 (Lys9) Antibody, biotin conjugate

merck millipore,默克密理博,ECM101,Millicoat™ Human Fibronectin Coated Strips (96-Wells) merck millipore,默克密理博,ECM101,Millicoat™ Human Fibronectin Coated Strips (96-Wells)

merck millipore,默克密理博,04-210,Anti-c-Jun (CT) Antibody, clone EP693Y, rabbit monoclonal merck millipore,默克密理博,04-210,Anti-c-Jun (CT) Antibody, clone EP693Y, rabbit monoclonal

merck millipore,默克密理博,14-751,Abl (Q252H) Protein, active, 10 µg merck millipore,默克密理博,14-751,Abl (Q252H) Protein, active, 10 µg

merck millipore,默克密理博,573112,SPDP merck millipore,默克密理博,573112,SPDP

merck millipore,默克密理博,ABN166,Anti-C-type lectin-like domain family 1 (CLECL1) Antibody merck millipore,默克密理博,ABN166,Anti-C-type lectin-like domain family 1 (CLECL1) Antibody

merck millipore,默克密理博,OP43,Anti-p53 (Ab-6) (Pantropic) Mouse mAb (DO-1) merck millipore,默克密理博,OP43,Anti-p53 (Ab-6) (Pantropic) Mouse mAb (DO-1)

merck millipore,默克密理博,AB1479P,Anti-Monocyte Chemotactic Protein-2 Antibody merck millipore,默克密理博,AB1479P,Anti-Monocyte Chemotactic Protein-2 Antibody

merck millipore,默克密理博,CA1026,Anti-Wilm's Tumor Protein Rabbit pAb merck millipore,默克密理博,CA1026,Anti-Wilm's Tumor Protein Rabbit pAb


whatman,沃特曼,nalgene,耐洁,merck millipore,默克密理愽,sartorius,赛多利斯,pall,颇尔
thermo fisher,赛默飞世尔,GE,MN,macherey-nagel,advantec,wheaton,brand,普兰德,welch,airtech


上海羽令过滤器材有限公司版权所有 Copyright ©  www.yl-guolv.com  Powered by 羽令集团—信息技术部