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merck millipore,默克密理博,MAB1937,Anti-Fibronectin Antibody, cell binding domain, clone 568
产品名称：Anti-Fibronectin Antibody, cell binding domain, clone 568
产品型号：MAB1937
Anti-Fibronectin Antibody, cell binding domain, clone 568 is an antibody against Fibronectin for use in IF, IP, RIA, WB, IH.
merck millipore,默克密理博,MAB1937,Anti-Fibronectin Antibody, cell binding domain, clone 568
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H IHC, WB M Ascites Monoclonal Antibody 描述 产品目录编号 MAB1937 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-Fibronectin Antibody, cell binding domain, clone 568 产品信息 格式 Ascites 演示 Liquid 应用 应用 Anti-Fibronectin Antibody, cell binding domain, clone 568 is an antibody against Fibronectin for use in IF, IP, RIA, WB, IH. 主要应用 - Immunohistochemistry
- Western Blotting
应用说明 Western blotting
Immunoprecipitation
RIA
Indirect immunofluorescence
Immunoperoxidase: For best results in tissue staining, use cryostat sections fixed with either acetone or 4% formaldehyde. Has not been tested on paraffin embedded tissue.
Optimal working dilutions must be determined by end user.生物信息 免疫原品种 Proteins secreted by cultured human embryonic fibroblasts. 表位 cell binding domain 克隆 568 宿主 Mouse 特异性 Reacts with whole human fibronectin and many of its proteolytic fragments. Specifically recognizes a synergistic cell-binding region located on the 8th type III repeat. Specificity established by immunoblotting with purified bacteria-expressed human fibronectin fragments 同种型 IgG1 品种反应性 Human 抗体类型 Monoclonal Antibody Entrez基因编号 - NM_212482.1
- NM_002026.2
- NM_054034.2
- NM_212474.1
- NM_212475.1
- NM_212476.1
- NM_212478.1
Entrez基因汇总 This gene encodes fibronectin, a glycoprotein present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix. Fibronectin is involved in cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. The gene has three regions subject to alternative splicing, with the potential to produce 20 different transcript variants. However, the full-length nature of some variants has not been determined. 基因符号 - FINC
- FN1
- DKFZp686H0342
- DKFZp686I1370
- MSF
- CIG
- LETS
- DKFZp686O13149
- FN
- DKFZp686F10164
UniProt编号 - P02751
UniProt汇总 FUNCTION: SwissProt: P02751 # Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Interaction with TNR mediates inhibition of cell adhesion and neurite outgrowth (By similarity).
SIZE: 2386 amino acids; 262607 Da
SUBUNIT: Mostly heterodimers or multimers of alternatively spliced variants, connected by 2 disulfide bonds near the carboxyl ends; to a lesser extent homodimers. Interacts with FBLN1, AMBP, TNR, LGALS3BP and COL13A1.
SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular matrix.
TISSUE SPECIFICITY: Plasma FN (soluble dimeric form) is secreted by hepatocytes. Cellular FN (dimeric or cross-linked multimeric forms), made by fibroblasts, epithelial and other cell types, is deposited as fibrils in the extracellular matrix. Ugl-Y1, Ugl-Y2 and Ugl-Y3 are found in urine.DEVELOPMENTAL STAGE: Ugl-Y1, Ugl-Y2 and Ugl-Y3 are present in the urine from 0 to 17 years of age.
PTM: Sulfated.
SIMILARITY: SwissProt: P02751 ## Contains 12 fibronectin type-I domains. & Contains 2 fibronectin type-II domains. & Contains 16 fibronectin type-III domains.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles. 包装信息 数量 100 µL
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