merck millipore,默克密理愽
  • merck millipore,默克密理博,MAB1682,Anti-Actinin α Antibody, clone AT6/172

  • merck millipore,默克密理博,MAB1682,Anti-Actinin α Antibody, clone AT6/172

    产品名称：Anti-Actinin α Antibody, clone AT6/172
    产品型号：MAB1682
    Anti-Actinin Antibody, α, clone AT6/172 detects level of Actinin & has been published & validated for use in IF, IP & WB.

    merck millipore,默克密理博,MAB1682,Anti-Actinin α Antibody, clone AT6/172

  • 产品介绍
  • merck millipore,默克密理博,MAB1682,Anti-Actinin α Antibody, clone AT6/172

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    HWBMAscitesMonoclonal Antibody
    描述
    产品目录编号 MAB1682
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-Actinin α Antibody, clone AT6/172
    产品信息
    格式 Ascites
    演示 Liquid
    应用
    应用 Anti-Actinin Antibody, α, clone AT6/172 detects level of Actinin & has been published & validated for use in IF, IP & WB.
    主要应用
    • Western Blotting
    应用说明 Immunoblotting: ~100kDa on SDS reducing gels

    Immunoprecipitation

    Immunofluorescence: methanol fixed cells

    Immunohistochemistry



    Optimal working dilutions must be determined by end user.
    生物信息
    免疫原品种 Human platelet protein
    表位 alpha
    克隆 AT6/172
    宿主 Mouse
    特异性 Human alpha actinin. This antibody recognizes an epitope in the N-terminal region of alpha-actinin, probably between residues 1-24.
    同种型 IgG1
    品种反应性 Human
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NM_001102.2
    Entrez基因汇总 Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene.
    基因符号
    • Alpha-actinin-1
    • ACTN1
    • FLJ40884
    UniProt编号
    • P12814
    UniProt汇总 FUNCTION: SwissProt: P12814 # F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein.
    SIZE: 892 amino acids; 103058 Da
    SUBUNIT: Homodimer; antiparallel. Interacts with MYOZ2, PDLIM2 and TTID and LPP.
    SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton. Cytoplasm, myofibril, sarcomere, Z-disk. Note=Colocalizes with MYOZ2 and PPP3CA at the Z-line of heart and skeletal muscle.
    SIMILARITY: SwissProt: P12814 ## Belongs to the alpha-actinin family. & Contains 1 actin-binding domain. & Contains 2 CH (calponin-homology) domains. & Contains 2 EF-hand domains. & Contains 4 spectrin repeats.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain frozen at -20°C for up to 12 months in undiluted aliquots. Avoid repeated freeze/thaw cycles.
    包装信息
    数量 100 µL

    merck millipore,默克密理博,MAB1682,Anti-Actinin α Antibody, clone AT6/172

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