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merck millipore,默克密理博,MABE544,Anti-MCM3, clone EPR7080, Rabbit Monoclonal Antibody
产品名称:Anti-MCM3, clone EPR7080, Rabbit Monoclonal Antibody
产品型号:MABE544
Please note that this product will not be available for sale after March 15, 2015. Please select one of the other antibodies against this target.
merck millipore,默克密理博,MABE544,Anti-MCM3, clone EPR7080, Rabbit Monoclonal Antibody
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 R, H, M IHC, WB Rb Unpurified Monoclonal Antibody 描述 产品目录编号 MABE544 描述 Anti-MCM3, clone EPR7080, Rabbit Monoclonal Antibody Alternate Names - p102
- DNA replication licensing factor MCM3
- DNA polymerase alpha holoenzyme-associated protein P1
- P1-MCM3
- RLF subunit beta
背景信息 DNA replication licensing factor MCM3, also known as DNA polymerase alpha holoenzyme-associated protein P1 or P1-MCM3 or RLF subunit beta or p102, and encoded by the gene name MCM3, is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and the recruitment of other DNA replication related proteins. MCM3 is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. MCM3 also interacts with, and thus is acetylated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. 产品信息 格式 Unpurified 演示 Rabbit monoclonal in buffer containing PBS with up to 0.1% sodium azide, 0.05% BSA, and 50% glycerol. 应用 应用 Please note that this product will not be available for sale after March 15, 2015. Please select one of the other antibodies against this target. 主要应用 - Immunohistochemistry
- Western Blotting
应用说明 Immunohistochemistry Analysis: A 1:100-250 dilution from a representative lot detected MCM3 in human colon tissue.
Produced in collaboration with Epitomics™生物信息 免疫原品种 Synthetic peptide corresponding to human MCM3. 克隆 EPR7080 浓缩 Please refer to lot specific datasheet. 宿主 Rabbit 同种型 IgG 品种反应性 RatHumanMouse Species Reactivity Note Human, Mouse, Rat 抗体类型 Monoclonal Antibody 基因符号 - MCM3
纯化方法 Unpurified UniProt编号 - P25205
产品使用声明 质量保证 Evaluated by Western Blotting in L6, C6, RAW264.7, PC-12, NIH/3T3, HeLa, K562, HepG2, U937 and HEK293 cell lysates.
Western Blotting Analysis: A 1:1,000-10,000 dilution of this antibody detected MCM3 in L6, C6, RAW264.7, PC-12, NIH/3T3, HeLa, K562, HepG2, U937, and HEK293 cell lysates.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.包装信息 数量 100 µL
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