• merck millipore,默克密理博,06-382,Anti-Calsequestrin Antibody, cardiac
  • merck millipore,默克密理博,06-382,Anti-Calsequestrin Antibody, cardiac

    产品名称:Anti-Calsequestrin Antibody, cardiac
    产品型号:06-382
    Anti-Calsequestrin Antibody, cardiac detects level of Calsequestrin & has been published & validated for use in IP, WB & IC.

    merck millipore,默克密理博,06-382,Anti-Calsequestrin Antibody, cardiac

  • 产品介绍
  • merck millipore,默克密理博,06-382,Anti-Calsequestrin Antibody, cardiac

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    Ca, M, RICC, WBRbPurifiedPolyclonal Antibody
    描述
    产品目录编号 06-382
    品牌系列 Upstate
    商名
    • Upstate
    描述 Anti-Calsequestrin Antibody, cardiac
    产品信息
    格式 Purified
    演示 0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%
    应用
    应用 Anti-Calsequestrin Antibody, cardiac detects level of Calsequestrin & has been published & validated for use in IP, WB & IC.
    主要应用
    • Immunocytochemistry
    • Western Blotting
    生物信息
    免疫原品种 Ten residue synthetic peptide corresponding to amino acids 39-48 (ESVSSDKVAQ) of mature canine calsequestrin (cardiac)
    宿主 Rabbit
    特异性 calsequestrin
    同种型 IgG
    品种反应性 CanineMouseRat
    Species Reactivity Note 'Predicted to react in humans due to high sequence homology (80%)
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NM_001232
    Entrez基因汇总 The protein encoded by this gene specifies the cardiac muscle family member of the calsequestrin family. Calsequestrin is localized to the sarcoplasmic reticulum in cardiac and slow skeletal muscle cells. The protein is a calcium binding protein that stores calcium for muscle function.
    基因符号
    • FLJ26321
    • CASQ2
    • PDIB2
    纯化方法 Protein A chromatography
    UniProt编号
    • O14958
    UniProt汇总 FUNCTION: SwissProt: O14958 # Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle. The release of calcium bound to calsequestrin through a calcium release channel triggers muscle contraction. Binds 40 to 50 moles of calcium (By similarity).
    SIZE: 399 amino acids; 46436 Da
    SUBCELLULAR LOCATION: Sarcoplasmic reticulum lumen. Note=This isoform of calsequestrin occurs in the sarcoplasmic reticulum's terminal cisternae luminal spaces of cardiac and slow skeletal muscle cells.
    DISEASE: SwissProt: O14958 # Defects in CASQ2 are the cause of an autosomal recessive form of stress-induced polymorphic ventricular tachycardia (VTSIP) [MIM:604772]; also known as catecholaminergic polymorphic ventricular tachycardia (CPVT). VTSIP is a genetic arrhythmogenic disorder characterized by stress-induced, bidirectional ventricular tachycardia that may degenerate into cardiac arrest and cause sudden death.
    SIMILARITY: SwissProt: O14958 ## Belongs to the calsequestrin family.
    产品使用声明
    质量保证 Routinely evaluated by immunoblot on a mouse heart preparation.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 2 years at -20°C
    包装信息
    数量 200 µg

    merck millipore,默克密理博,06-382,Anti-Calsequestrin Antibody, cardiac

上一件merck millipore产品:merck millipore,默克密理博,14-584M,PAK4 Protein, active, 250 µg
下一件merck millipore产品:merck millipore,默克密理博,506181,p75NTR Signaling Inhibitor, Cell-permeable, TAT-Pep5 - Calbiochem



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