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merck millipore,默克密理博,MAB1087,Anti-Eosinophil Peroxidase Antibody, clone AHE-1
产品名称:Anti-Eosinophil Peroxidase Antibody, clone AHE-1
产品型号:MAB1087
Detect Eosinophil Peroxidase using this Anti-Eosinophil Peroxidase Antibody, clone AHE-1 validated for use in IC.
merck millipore,默克密理博,MAB1087,Anti-Eosinophil Peroxidase Antibody, clone AHE-1
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H ICC M Ascites Monoclonal Antibody 描述 产品目录编号 MAB1087 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-Eosinophil Peroxidase Antibody, clone AHE-1 产品信息 格式 Ascites 演示 Ascites fluid. 应用 应用 Detect Eosinophil Peroxidase using this Anti-Eosinophil Peroxidase Antibody, clone AHE-1 validated for use in IC. 主要应用 - Immunocytochemistry
应用说明 Final working dilutions must be determined by end user. 生物信息 克隆 AHE-1 宿主 Mouse 特异性 Reacts specifically with human eosinophil peroxidase from eosinophils among peripheral blood cells. Eosinophil peroxidase is felt to play an important role in eosinophil function and perhaps endothelial injury in hypereosinophilic states. 同种型 IgG1 品种反应性 Human 抗体类型 Monoclonal Antibody Entrez基因编号 - NM_000502.2
基因符号 - Eosinophil peroxidase heavy chain].
- EPX
- EPO
- EPX-PEN
- EPER
- EPP
- EC 1.11.1.7 [Contains: Eosinophil peroxidase light chain
UniProt编号 - P11678
UniProt汇总 COFACTOR: Binds 1 calcium ion per heterodimer (By similarity). & Binds 1 heme B (iron-protoporphyrin IX) covalently through ester linkages to hydroxylated methyl groups formed auto- catalytically with hydrogen peroxide at the heme C-1 and C-5 positions. The ester linkage to Asp-232 was observed in 30% of the chains.
SIZE: 715 amino acids; 81040 Da
SUBUNIT: Tetramer of two light chains and two heavy chains.
SUBCELLULAR LOCATION: Cytoplasmic granule. Note=Cytoplasmic granules of eosinophils.
DISEASE: SwissProt: P11678 # Defects in EPX are the cause of eosinophil peroxidase deficiency (EPD) [MIM:261500]. EPD is an autosomal recessive defect where anomalous eosinophils are characterized by nuclear hypersegmentation, hypogranulation, and negative peroxidase and phospholipid staining.
SIMILARITY: SwissProt: P11678 ## Belongs to the peroxidase family. XPO subfamily.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain at -20°C in aliquots for up to 12 months. Avoid repeated freeze/thaw cycles. 包装信息 数量 100 µL
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