merck millipore,默克密理博,05-623,Anti-RNA polymerase II Antibody, clone CTD4H8

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merck millipore,默克密理博,05-623,Anti-RNA polymerase II Antibody, clone CTD4H8
产品名称：Anti-RNA polymerase II Antibody, clone CTD4H8
产品型号：05-623
Anti-RNA polymerase II Antibody, clone CTD4H8 is a high quality Mouse Monoclonal Antibody for the detection of RNA polymerase II & has been validated in ChIP & WB.

merck millipore,默克密理博,05-623,Anti-RNA polymerase II Antibody, clone CTD4H8

产品介绍

merck millipore,默克密理博,05-623,Anti-RNA polymerase II Antibody, clone CTD4H8

重要规格表

品种反应性	主要应用	宿主	格式	抗体类型
Yeast (S. cerevisiae), H, R, M	WB	M	Purified	Monoclonal Antibody

描述
产品目录编号	05-623
品牌系列	Upstate
商名	Upstate
描述	Anti-RNA polymerase II Antibody, clone CTD4H8
背景信息	RNA polymerase II (Pol II) is a multi-subunit enzyme responsible for the transcription of protein-coding genes. Transcription initiation requires recruitment of the complete transcription machinery to a promoter via solicitation by activators and chromatin remodeling factors. Pol II can coordinate 10 to 14 subunits. This complex interacts with the promoter regions of genes and a variety of elements and transcription factors. The DNA binding domain of the polymerase is a groove where TFIIB orients the DNA for unwinding and transcription.

产品信息
格式	Purified
控制	A431 nuclear extract.
演示	Purified mouse IgG1 in buffer containing 0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%.

应用
应用	Anti-RNA polymerase II Antibody, clone CTD4H8 is a high quality Mouse Monoclonal Antibody for the detection of RNA polymerase II & has been validated in ChIP & WB.
主要应用	Western Blotting

生物信息
免疫原品种	Peptide containing 10 repeats of YSPT[pS]PS corresponding to the carboxyl-terminal domain of RNA polymerase II.
克隆	CTD4H8
浓缩	Please refer to the Certificate of Analysis for the lot-specific concentration.
宿主	Mouse
特异性	This antibody recognizes Phospho- and non-phospho-RNA polymerase II.
同种型	IgG1
品种反应性	Yeast (S. cerevisiae)HumanRatMouse
Species Reactivity Note	Human, mouse, rat and yeast.
抗体类型	Monoclonal Antibody
Entrez基因编号	NP_000928
纯化方法	Protein G chromatography
UniProt编号	P24928

产品使用声明
质量保证	Routinely evaluated by western blot on HeLa nuclear extracts. Western Blot Analysis: 0.05-1 μg/mL of this lot detected RNA polymerase II in HeLa nuclear extracts. 0.1-2 μg/mL of a previous lot detected RNA polymerase II in 3T3 nuclear extracts
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.

储存和货运信息

存储条件

Stable for 1 year at -20°C from date of receipt.

Handling Recommendations:
Upon receipt, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.