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品种 宿主细胞 蛋白靶 Human Chem-1 CCR2B 描述 产品目录编号 HTS007M 品牌系列 Chemicon®
商名 - Chemicon
- ChemiScreen
描述 ChemiSCREEN™ CCR2B Membrane Preparation 产品信息 格式 Membranes 应用 应用 Human CCR2B GPCR membrane prepation for Radioligand binding Assays. 生物信息 品种 Human 品种反应性 Human Entrez基因编号 - NM_000648.2
- NM_000647.4
Entrez基因汇总 This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The receptors encoded by this gene mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This gene is located in the chemokine receptor gene cluster region. Two alternatively spliced transcript variants are expressed by the gene. 基因符号 - CKR2B
- CCR2
- CC-CKR-2
- CCR2A
- CCR-2
- CKR2
- CKR2A
- MCP-1-R
- CCR2B
- CMKBR2
- CD192
- MCP-1
GPCR类别 A 宿主细胞 Chem-1 蛋白靶 CCR2B 靶子系列 Chemokine UniProt编号 - P41597
UniProt汇总 FUNCTION: SwissProt: P41597 # Receptor for the MCP-1, MCP-3 and MCP-4 chemokines. Transduces a signal by increasing the intracellular calcium ions level. Alternative coreceptor with CD4 for HIV-1 infection.
SIZE: 374 amino acids; 41915 Da
SUBUNIT: Binds to HIV-1 Tat.
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
PTM: N-glycosylated.
SIMILARITY: SwissProt: P41597 ## Belongs to the G-protein coupled receptor 1 family.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
包装信息 数量 200 assays
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