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来源 纯度 HumanKine growth factors are expressed in a proprietary human 293 protein expression system and are manufactured without the use of any animal products and are considered Xeno-Free. Product is endotoxin free (<0.1 ng/μg of protein (<1 EU/μg) and greater than 95% pure by SDS-PAGE. 描述 产品目录编号 GF440 商名 - HumanKine®
描述 HumanKine® TGF beta 2, Human Recombinant Xeno-Free Alternate Names - Transforming Growth Factor-β2
- TGFb2
- TGFbII
- TGFB
背景信息 Transforming Growth Factor- beta2 (TGFb2) is a member of a superfamily of homologous, disulfide-linked, homodimeric proteins that regulate the proliferation and differentiation of normal and transformed cells. TGfb2 regulates proliferation, differentiation, adhesion, migration, and other functions in many cell types by transducing their signal through combinations of transmembrane type I and type II receptors (TGFBR1 and TGFBR2) and their downstream effectors, the SMAD proteins. Disruption of the TGFB/SMAD pathway has been implicated in a variety of human cancers. 产品信息 配方 演示 Product is presented in 50mM NaOAc pH 4.5 and filtered through a 0.2 micron filter before lyophilization. 生物信息 纯度 Product is endotoxin free (<0.1 ng/μg of protein (<1 EU/μg) and greater than 95% pure by SDS-PAGE. 来源 HumanKine growth factors are expressed in a proprietary human 293 protein expression system and are manufactured without the use of any animal products and are considered Xeno-Free. UniProt编号 - P61812
产品使用声明 质量保证 Bioactivity assay: Determined by the dose dependent inhibition of IL-4 induced proliferation of mouse HT-2 cells (BALB/c spleen activated by sheep erythrocytes in the presence of IL-2). ED50 is typically 0.1-0.5 ng/ml. 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Store at -20°C for up to 4 months from date of receipt. Further dilutions should be made into appropriate buffer or medium to which protein has been added. 包装信息 数量 5 µg
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