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品种反应性 主要应用 宿主 格式 抗体类型 H WB M Purified Monoclonal Antibody 描述 产品目录编号 05-608 品牌系列 Upstate
商名 - Upstate
描述 Anti-PLD Antibody, clone SKB2 产品信息 格式 Purified 演示 0.1M Tris-glycine, pH 7.4, 0.15M NaCl, and 0.05% sodium azide before the addition of glycerol to 30% 应用 应用 Detect PLD using this Anti-PLD Antibody, clone SKB2 validated for use in IP & WB. 主要应用 - Western Blotting
生物信息 免疫原品种 GST fusion-protein corresponding to residues 326-504 of human PLD 1 克隆 clone SKB2 宿主 Mouse 特异性 PLD 1 and PLD 2 同种型 IgG 品种反应性 Human 抗体类型 Monoclonal Antibody Entrez基因编号 - NM_002662
Entrez基因汇总 Phosphatidylcholine (PC)-specific phospholipases D (PLDs; EC 3.1.4.4) catalyze the hydrolysis of PC to produce phosphatidic acid and choline. A range of agonists acting through G protein-coupled receptors and receptor tyrosine kinases stimulate this hydrolysis. PC-specific PLD activity has been implicated in numerous cellular pathways, including signal transduction, membrane trafficking, and the regulation of mitosis (Hammond et al., 1995 [PubMed 8530346]).[supplied by OMIM] 基因符号 - hPLD1
- PLD1
纯化方法 Protein G chromatography UniProt编号 - Q13393
UniProt汇总 FUNCTION: SwissProt: Q13393 # Implicated as a critical step in numerous cellular pathways, including signal transduction, membrane trafficking, and the regulation of mitosis. May be involved in the regulation of perinuclear intravesicular membrane traffic (By similarity).
SIZE: 1074 amino acids; 124184 Da
SUBUNIT: Interacts with PIP5K1A.
SUBCELLULAR LOCATION: Cytoplasm, perinuclear region (By similarity). Endoplasmic reticulum (By similarity). Golgi apparatus (By similarity). Late endosome (By similarity).
TISSUE SPECIFICITY: Expressed abundantly in the pancreas and heart and at high levels in brain, placenta, spleen, uterus and small intestine.
SIMILARITY: SwissProt: Q13393 ## Belongs to the phospholipase D family. & Contains 1 PH domain. & Contains 2 PLD phosphodiesterase domains. & Contains 1 PX (phox homology) domain.产品使用声明 质量保证 routinely evaluated by immunoblot on RIPA lysates from HeLa cells 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 2 years at -20°C 包装信息 数量 100 µg
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下一件merck millipore产品：merck millipore,默克密理博,ABC499,Anti-Tropomyosin Antibody, isoforms 5a, 5b, Br2, Br3
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