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merck millipore,默克密理博,GF168,BMP-6 Protein, Human Recombinant
产品名称:BMP-6 Protein, Human Recombinant
产品型号:GF168
The Bone Morphogenetic Protein 6 also known as Vgr-1 protein, is one of at least 15 structurally & functionally related BMPs which are members of the TGF-β superfamily.
merck millipore,默克密理博,GF168,BMP-6 Protein, Human Recombinant
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重要规格表
来源 纯度 HEK293 Cells Product is endotoxin free (< 0.1ng/μg of protein (<1EU/μg) and greater than 95% pure by SDS-PAGE gel and HPLC analyses 描述 产品目录编号 GF168 描述 BMP-6 Protein, Human Recombinant Alternate Names - VG-1-related protein
- Bone Morphogenetic Protein 6
- BMP6
- VRR-1
背景信息 Bone Morphogenetic Protein 6 (BMP-6), also known as Vgr-1, is one of at least 15 structurally and functionally related BMPs which are members of the transforming growth factor β (TGF-β) superfamily. TGF-β family members are key modulators of cell proliferation, differentiation, matrix synthesis, and apoptosis. As implied by their name, BMPs initiate, promote, and regulate the development, growth and remodeling of bone and cartilage. In addition to this role, BMPs are also involved in prenatal development and postnatal growth, remodeling and maintenance of a variety of other tissues and organs. Increasing evidence indicates that BMP-Smad signaling has a tumor suppressing activity and that BMPs can inhibit tumor growth. BMP-6 is abnormally expressed in breast cancer cell lines; however, its function in promoting breast cancer development is unknown. Recombinant human BMP-6 is a 26.2 kDa homodimeric glycoprotein consisting of two 117 amino acid subunits, which correspond to amino acid residues 397 to 513 of the full-length BMP-6 precursor. 产品信息 演示 Product is filtered through a 0.2 micron filter before lyophilization. 应用 应用 The Bone Morphogenetic Protein 6 also known as Vgr-1 protein, is one of at least 15 structurally & functionally related BMPs which are members of the TGF-β superfamily. 生物信息 纯度 Product is endotoxin free (< 0.1ng/μg of protein (<1EU/μg) and greater than 95% pure by SDS-PAGE gel and HPLC analyses 来源 HEK293 Cells 交叉反应性 None UniProt编号 - P22004
产品使用声明 质量保证 Bioactivity assay: Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expected ED50 this effect is 0.03-0.06 μg/ml. 储存和货运信息 存储条件 Store at -20°C for up to 6 months from date of receipt. 包装信息 数量 10 µg
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