• merck millipore,默克密理博,ABT242,Anti-Galectin-4 Antibody
  • merck millipore,默克密理博,ABT242,Anti-Galectin-4 Antibody

    产品名称:Anti-Galectin-4 Antibody
    产品型号:ABT242
    This Anti-Galectin-4 Antibody is validated for use in Western Blotting and Immunohistochemistry for the detection of Galectin-4.

    merck millipore,默克密理博,ABT242,Anti-Galectin-4 Antibody

  • 产品介绍
  • merck millipore,默克密理博,ABT242,Anti-Galectin-4 Antibody

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    HIHC, WBRbAffinity PurifiedPolyclonal Antibody
    描述
    产品目录编号 ABT242
    描述 Anti-Galectin-4 Antibody
    Alternate Names
    • Lactose-binding lectin 4
    • Galectin-4
    • Gal-4
    • Antigen NY-CO-27
    • L-36 lactose-binding protein
    • L36LBP
    背景信息 Galectin 4, or GAL-4, is another member of the Galectin family. Galectins are carbohydrate binding proteins that appear important in cell-cell contact, cell migration, and cell to cell signaling in both normal and disease (cancerous) tissues. Galectin 4 differs from its sister family members in the range of carbohydrate substrates that it binds. Galentin-4 is synthesized as a cytosolic protein, but can be externalized. During development and in adult normal tissues, galectin-4 is expressed only in the alimentary tract, from the tongue to the large intestine. It is often found in relatively insoluble complexes as a component of either adherent junctions or lipid rafts in the microvillus membrane, and it has been proposed to stabilize these structures. Strong expression of galectin-4 can be induced, however, in cancers from other tissues including breast and liver. Also, Galectin-4 appears to specifically bind CD3 on activated T-cells in the gut and regulate their activity via calpain mediated apoptosis.
    产品信息
    格式 Affinity Purified
    演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
    应用
    应用 This Anti-Galectin-4 Antibody is validated for use in Western Blotting and Immunohistochemistry for the detection of Galectin-4.
    主要应用
    • Immunohistochemistry
    • Western Blotting
    应用说明 Western Blotting Analysis: A 1:1,000 dilution from a representative lot detected Galectin-4 in 10 µg of Colo320 cell lysate.
    Western Blotting Analysis: A 1:1,000 dilution from a representative lot detected Galectin-4 in 10 µg of human small intestine tissue lysate.
    Immunohistochemistry Analysis: A 1:250 dilution from a representative lot detected Galectin-4 in human stomach tissue.
    生物信息
    免疫原品种 KLH-conjugated linear peptide corresponding to human Galectin-4 near the N-terminal.
    表位 near N-terminal
    浓缩 Please refer to lot specific datasheet.
    宿主 Rabbit
    品种反应性 Human
    Species Reactivity Note Human. Predicted to react with Monkey, Chimpanzee, Primate, Rhesus Macaque, Feline based on 100% sequence homology.
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NP_006140
    基因符号
    • LGALS4
    纯化方法 Affinity purified
    UniProt编号
    • ">P56470
    产品使用声明
    质量保证 Evaluated by Western Blotting in HT-29 cell lysate.

    Western Blotting Analysis: A 1:1,000 dilution of this antibody detected Galectin-4 in 10 µg of HT-29 cell lysate.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 1 year at 2-8°C from date of receipt.
    包装信息
    数量 100 µL

    merck millipore,默克密理博,ABT242,Anti-Galectin-4 Antibody

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