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- merck millipore,默克密理博,ABT242,Anti-Galectin-4 Antibody
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H IHC, WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABT242 描述 Anti-Galectin-4 Antibody Alternate Names - Lactose-binding lectin 4
- Galectin-4
- Gal-4
- Antigen NY-CO-27
- L-36 lactose-binding protein
- L36LBP
背景信息 Galectin 4, or GAL-4, is another member of the Galectin family. Galectins are carbohydrate binding proteins that appear important in cell-cell contact, cell migration, and cell to cell signaling in both normal and disease (cancerous) tissues. Galectin 4 differs from its sister family members in the range of carbohydrate substrates that it binds. Galentin-4 is synthesized as a cytosolic protein, but can be externalized. During development and in adult normal tissues, galectin-4 is expressed only in the alimentary tract, from the tongue to the large intestine. It is often found in relatively insoluble complexes as a component of either adherent junctions or lipid rafts in the microvillus membrane, and it has been proposed to stabilize these structures. Strong expression of galectin-4 can be induced, however, in cancers from other tissues including breast and liver. Also, Galectin-4 appears to specifically bind CD3 on activated T-cells in the gut and regulate their activity via calpain mediated apoptosis. 产品信息 格式 Affinity Purified 演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 This Anti-Galectin-4 Antibody is validated for use in Western Blotting and Immunohistochemistry for the detection of Galectin-4. 主要应用 - Immunohistochemistry
- Western Blotting
应用说明 Western Blotting Analysis: A 1:1,000 dilution from a representative lot detected Galectin-4 in 10 µg of Colo320 cell lysate.
Western Blotting Analysis: A 1:1,000 dilution from a representative lot detected Galectin-4 in 10 µg of human small intestine tissue lysate.
Immunohistochemistry Analysis: A 1:250 dilution from a representative lot detected Galectin-4 in human stomach tissue.生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to human Galectin-4 near the N-terminal. 表位 near N-terminal 浓缩 Please refer to lot specific datasheet. 宿主 Rabbit 品种反应性 Human Species Reactivity Note Human. Predicted to react with Monkey, Chimpanzee, Primate, Rhesus Macaque, Feline based on 100% sequence homology. 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_006140
基因符号 - LGALS4
纯化方法 Affinity purified UniProt编号 -
">P56470
产品使用声明 质量保证 Evaluated by Western Blotting in HT-29 cell lysate.
Western Blotting Analysis: A 1:1,000 dilution of this antibody detected Galectin-4 in 10 µg of HT-29 cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µL
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