merck millipore,默克密理博,FCMAB331F,Milli-Mark™ Anti-RNA Poly II-FITC Antibody, clone CTD4H8

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Merck Millipore 默克密理愽

品种反应性	主要应用	宿主	格式	抗体类型
H	FC	M	FITC	Monoclonal Antibody

描述
产品目录编号	FCMAB331F
商名	Milli-Mark
描述	Milli-Mark™ Anti-RNA Poly II-FITC Antibody, clone CTD4H8
背景信息	RNA polymerase II (Pol II) is a multi-subunit enzyme responsible for the transcription of protein-coding genes. Transcription initiation requires recruitment of the complete transcription machinery to a promoter via solicitation by activators and chromatin remodeling factors. Pol II can coordinate 10 to 14 subunits. This complex interacts with the promoter regions of genes and a variety of elements and transcription factors.

产品信息
格式	FITC
控制	HeLa Cells
演示	Purified mouse monoclonal IgG1κ conjugated to FITC in PBS with 0.1% sodium azide and 15 mg/mL BSA.

应用
应用	Milli-Mark Anti-RNA Poly II-FITC Antibody, clone CTD4H8 detects level of RNA Poly II & has been published & validated for use in FC.
主要应用	Flow Cytometry

生物信息
免疫原品种	Peptide corresponding to the carboxyl-terminal domain of RNA polymerase II.
表位	carboxyl-terminal domain
克隆	CTD4H8
宿主	Mouse
特异性	Antibody recognizes human RNA Polymerase II.
同种型	IgG1κ
品种反应性	Human
Species Reactivity Note	Tested and passed on Human. Unconjugated antibody (Cat. No. 05-623) is known to react on Rat, Mouse, Yeast (S. cerevisiae).
抗体类型	Monoclonal Antibody
Entrez基因编号	NP_000928
Entrez基因汇总	This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA ineukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential forpolymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA. [provided by RefSeq]
纯化方法	Protein G Purified
UniProt编号	P24928

产品使用声明
质量保证	Evaluated by flow cytometry using HeLa cells.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Maintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.

包装信息
数量	100 tests

merck millipore,默克密理博,FCMAB331F,Milli-Mark™ Anti-RNA Poly II-FITC Antibody, clone CTD4H8

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