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可用的分析物 品种反应性 主要应用 检测方法 FGF-21 H ELISA Colorimetric, Fluorescent 描述 产品目录编号 EZHFGF21-19K 描述 Human FGF-21 ELISA Kit 背景信息 Recent studies have demonstrated that fibroblast growth factor 21 (FGF-21), a liver derived protein, is able to increase glucose uptake, as well as lower plasma triglyceride levels in an insulin-independent manner. FGF-21 suppresses glucagon release, thereby increasing insulin sensitivity, and reduces the amount of insulin production required by pancreatic β-cells. Unlike insulin, which works in a rapid, hormone-like manner, FGF-21 activity requires several hours, indicating changes in gene expression. While insulin functions through GLUT4 translocation, FGF-21 has been shown to act primarily through the upregulation of adipocyte GLUT1, a transporter that allows glucose to move from the blood into cells even in the absence of insulin. In addition, no significant weight gain was observed when FGF-21 was injected into animals, and mice that had been genetically engineered to overexpress FGF-21 weighed less and had less adipose tissue than the normal controls. 产品信息 检测方法 ColorimetricFluorescent 精度(%) - Inter-assay: < 9%
- Intra-assay: < 6%
应用 应用 This Human FGF-21 ELISA Kit is used to measure & quantify FGF-21 levels in Metabolism & Inflammation & Immunology research. 主要应用 - ELISA
应用说明 This is a 3-hour assay requiring 50 μL of sample. 生物信息 特异性 No significant cross-reactivity to the cytokines and metabolic hormones tested was observed. 品种反应性 Human 可用的分析物 - FGF-21
准确度 - 83 – 99%
理化信息 稀释的线性 Serum: 95.7–104.7% Plasma: 95–117% 标准曲线范围 - 31.3– 2000 pg/mL
产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
包装信息 数量 96-well strip plate
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