• merck millipore,默克密理博,ECM660,Pseudopodia Purification Kit
  • merck millipore,默克密理博,ECM660,Pseudopodia Purification Kit

    产品名称:Pseudopodia Purification Kit
    产品型号:ECM660
    The Pseudopodia Purification Kit is a novel system designed to specifically isolate & purify extending pseudopodia proteins from the cell body.

    merck millipore,默克密理博,ECM660,Pseudopodia Purification Kit

  • 产品介绍
  • merck millipore,默克密理博,ECM660,Pseudopodia Purification Kit

    重要规格表

    主要应用
    ACT
    描述
    产品目录编号 ECM660
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Pseudopodia Purification Kit
    概述 Chemotaxis, or directed cell movement is a fundamental cellular process, necessary for embryonic development, angiogenesis, wound healing, and immune responses, as well as pathological events associated with inflammation and cancer metastasis [Lauffenburger & Horwitz, 1996]. Prior to cell body translocation or chemotaxis, a cell must first extend a dominant pseudopodium (lamellipodium) in the direction of the chemoattractant gradient [Lauffenburger & Horwitz, 1996; Parent & Devreotes, 1999]. Once a dominant pseudopodium is formed, cell movement can begin in the direction of the gradient. Formation of a directional pseudopodium is tightly controlled by signal transduction mechanisms that temporally and spatially regulate changes in focal adhesions, microtubules, and the actin/myosin cytoskeleton [Ridley et al., 1992; Schmidt et al., 1993; Manes et al., 1999; Nobes & Hall, 1999; Eddy et al., 2000].

    The CHEMICON Pseudopodia Purification Kit is a novel system designed to specifically isolate and purify extending pseudopodia proteins from the cell body [Cho & Klemke, 2002]. This Kits provides a quick and efficient system to purify pseudopodia proteins and their responses to various natural or synthetic compounds that specifically impact the microenvironment of the pseudopodial organelle including signaling processes, integrins or other adhesion receptors, and unique gene products. This kit provides a novel method for pseudopodia protein purification; identify signaling complex formation as a result of chemotaxis stimuli.

    For Research Use Only; Not for use in diagnostic procedures
    产品信息
    部件
    • Cotton Swabs - (Catalog No. 10202) 14 swabs
    • Pseudopodia Purification Inserts - (Catalog No. 71608) 1 X 6 well plate containing 6 X 24mm 3.0-micrometer transwells.
    • Western Blot Lysis Buffer - (Catalog No. 71606) 20 mL of 50 mM Tris, pH 7.4, 5 mM EDTA, 150 mM NaCl, 1% SDS
    • Immunoprecipitation Buffer - (Catalog No. 71601) 20 mL of 50 mM Tris, pH 7.4, 5 mM EDTA, 150 mM NaCl, 1% Triton-X-100
    • Cell Scrapers - (Catalog No.71603) 3 each
    • Forceps - (Catalog No. 10203) 1 each
    应用
    应用 The Pseudopodia Purification Kit is a novel system designed to specifically isolate & purify extending pseudopodia proteins from the cell body.
    主要应用
    • Activity Assay
    生物信息
    品种反应性 Human
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Store Kit and Materials at 2-8ºC until their expiration date
    包装信息
    数量 1 kit

    merck millipore,默克密理博,ECM660,Pseudopodia Purification Kit

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