merck millipore,默克密理愽
  • merck millipore,默克密理博,CKT1MAG-97K,MILLIPLEX MAP Canine Kidney Toxicity Expanded Magnetic Bead Panel 1, CKT1MAG-97K

  • merck millipore,默克密理博,CKT1MAG-97K,MILLIPLEX MAP Canine Kidney Toxicity Expanded Magnetic Bead Panel 1, CKT1MAG-97K

    产品名称：MILLIPLEX MAP Canine Kidney Toxicity Expanded Magnetic Bead Panel 1, CKT1MAG-97K
    产品型号：CKT1MAG-97K
    The analytes available for this multiplex kit are: Clusterin, Cystatin C, Kidney Injury Molecule-1 (KIM-1), IL-8, Lipocalin-2/NGAL, MCP-1, Osteopontin (OPN).

    merck millipore,默克密理博,CKT1MAG-97K,MILLIPLEX MAP Canine Kidney Toxicity Expanded Magnetic Bead Panel 1, CKT1MAG-97K

  • 产品介绍
  • merck millipore,默克密理博,CKT1MAG-97K,MILLIPLEX MAP Canine Kidney Toxicity Expanded Magnetic Bead Panel 1, CKT1MAG-97K

    重要规格表

    可用的分析物 品种反应性 主要应用 检测方法
    Osteopontin, Clusterin, Cystatin C, KIM-1, IL-8, Lipocalin-2/NGAL, MCP-1CaMplexLuminex xMAP
    描述
    产品目录编号 CKT1MAG-97K
    商名
    • MILLIPLEX
    描述 MILLIPLEX® MAP Canine Kidney Toxicity Expanded Magnetic Bead Panel 1, CKT1MAG-97K
    概述 The MILLIPLEX® MAP Canine Kidney Toxicity Expanded Magnetic Bead Panel 1, contains all the components necessary to measure the following seven biomarkers in any combination using Luminex® xMAP® technology: Clusterin, Cystatin C, Kidney Injury Molecule-1 (KIM-1), IL-8, Lipocalin-2/NGAL, MCP-1, Osteopontin (OPN). The kit uses a 96-well format, contains a lyophilized standard cocktail, two quality controls and can measure up to 38 urine samples in duplicate.
    背景信息 As one of the leading causes of drug candidate attrition, toxicity research is receiving more attention, especially in the search of sensitive, organ-specific toxicity biomarkers.

    In pharmaceutical and chemical industries, the kidney is routinely assessed during toxicity evaluations. The importance of the kidney as a central detoxification organ leads to a high exposure of renal tissue to drugs, reactive metabolites, and environmental compounds. Traditional markers for assessing renal toxicity, such as blood urea nitrogen (BUN) and serum creatinine, are insensitive and non-specific. For improved, non-invasive detection of acute nephrotoxicity, a panel of novel urinary kidney biomarkers has been identified and validated for preclinical studies in relevant animal species.

    EMD Millipore provides an expanded valuable research assay to investigate multiple biomarkers of kidney injury in canine urine samples using the Luminex xMAP® instrument platform. The new MILLIPLEX® MAP Canine Kidney Toxicity Expanded Magnetic Bead Panel 1 not only contains the three important biomarkers from the original Canine Kidney Toxicity Panel 1 (Clusterin, Cystatin C and KIM-1), but it also includes specific and sensitive assays for 4 more important nephrotoxicity biomarkers.
    产品信息
    检测方法 Luminex xMAP
    配置 Design your multiplex kit by choosing analytes.
    精度（%）
    • Intra-Assay: < 10
    • Inter-assay: < 15
    板面类型 MAGNETIC Toxicity
    应用
    应用 The analytes available for this multiplex kit are: Clusterin, Cystatin C, Kidney Injury Molecule-1 (KIM-1), IL-8, Lipocalin-2/NGAL, MCP-1, Osteopontin (OPN).
    主要应用
    • Multiplexing
    应用说明 • Customers should determine the optimal dilution factor for their samples. Our recommendations are based on urine samples from normal subjects.
    • This assay requires 25 µL of 1:2 diluted urine sample per well in kit Assay Buffer (please dilute per protocol instructions).
    • This is a 2 hour assay.
    生物信息
    特异性 There was no or negligible cross-reactivity between the antibodies for an analyte and any of the other analytes within a panel.
    品种反应性 Canine
    可用的分析物
    • Osteopontin
    • Clusterin
    • Cystatin C
    • KIM-1
    • IL-8
    • Lipocalin-2/NGAL
    • MCP-1
    化验面板 Everything you need in a single kit.
    交叉反应性 There was no or negligible cross-reactivity between the antibodies for an analyte and any of the other analytes within a panel.
    准确度
    • 89% - 107%
    理化信息
    灵敏度
    • See kit protocol for individual analytes sensitivities.
    • KIM-1: 0.670 pg/mL (MinDC +2SD)
    • All other analytes: 0.005- 0.630 ng/mL (MinDC +2SD)
    稀释的线性 Contact technical support for this information
    标准曲线范围
    • Osteopontin: 0.01 – 10 ng/mL
    • KIM-1: 1.0 – 700 pg/mL
    • Clusterin: 1.4 – 1,000 ng/mL
    • Cystatin C: 0.01 – 10 ng/mL
    • IL-8: 0.07 – 50 ng/mL
    • Lipocalin-2/NGAL: 0.03 – 20 ng/mL
    • MCP-1: 0.07 – 50 ng/mL
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Recommended storage for kit components is 2 - 8°C.
    包装信息
    数量 96-well plate

    merck millipore,默克密理博,CKT1MAG-97K,MILLIPLEX MAP Canine Kidney Toxicity Expanded Magnetic Bead Panel 1, CKT1MAG-97K

上一件merck millipore产品：merck millipore,默克密理博,512533,MKLP-2 Inhibitor, Paprotrain - Calbiochem
下一件merck millipore产品：merck millipore,默克密理博,341597,FGF-II, Mouse, Recombinant, E. coli


相关产品

merck millipore,默克密理博,361524,GSK-3β, His•Tag, Human, Recombinant, E. coli merck millipore,默克密理博,361524,GSK-3β, His•Tag, Human, Recombinant, E. coli

merck millipore,默克密理博,04-419,Anti-phospho-Rsk1 (Thr359/Ser363) Antibody, rabbit monoclonal merck millipore,默克密理博,04-419,Anti-phospho-Rsk1 (Thr359/Ser363) Antibody, rabbit monoclonal

merck millipore,默克密理博,AB2953,Anti-ATG3 Antibody merck millipore,默克密理博,AB2953,Anti-ATG3 Antibody

merck millipore,默克密理博,IP02,Protein A Agarose Suspension merck millipore,默克密理博,IP02,Protein A Agarose Suspension

merck millipore,默克密理博,512533,MKLP-2 Inhibitor, Paprotrain - Calbiochem merck millipore,默克密理博,512533,MKLP-2 Inhibitor, Paprotrain - Calbiochem

merck millipore,默克密理博,341597,FGF-II, Mouse, Recombinant, E. coli merck millipore,默克密理博,341597,FGF-II, Mouse, Recombinant, E. coli

merck millipore,默克密理博,FCMAB135F,Milli-Mark Anti-BMP-7-FITC Antibody, clone 2A10 merck millipore,默克密理博,FCMAB135F,Milli-Mark Anti-BMP-7-FITC Antibody, clone 2A10

merck millipore,默克密理博,324800,Epoxomicin, Synthetic - Calbiochem merck millipore,默克密理博,324800,Epoxomicin, Synthetic - Calbiochem

merck millipore,默克密理博,MAB1935,Anti-Fibronectin Antibody, CT, clone 868A11 merck millipore,默克密理博,MAB1935,Anti-Fibronectin Antibody, CT, clone 868A11

merck millipore,默克密理博,5871,Thiamine, Hydrochloride - CAS 67-03-8 - Calbiochem merck millipore,默克密理博,5871,Thiamine, Hydrochloride - CAS 67-03-8 - Calbiochem


whatman,沃特曼,nalgene,耐洁,merck millipore,默克密理愽,sartorius,赛多利斯,pall,颇尔
thermo fisher,赛默飞世尔,GE,MN,macherey-nagel,advantec,wheaton,brand,普兰德,welch,airtech


上海羽令过滤器材有限公司版权所有 Copyright ©  www.yl-guolv.com  Powered by 羽令集团—信息技术部